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Table 5 Hemodynamic variables before and after volume expansion in responder and non-responder patients

From: Changes in dynamic arterial elastance induced by volume expansion and vasopressor in the operating room: a prospective bicentre study

  Responders (n = 21) Non-responders (n = 35)
Before VE After VE P1 Before VE After VE P2 P3
Heart rate (bpm) 62 [58–72] 60 [54–71] 0.0028 65 [57–74] 60 [56–71] < 0.0001 0.71
SAP (mmHg) 77 [66–80] 86 [79–93] 0.0001 82 [79–87] 80 [77–86] 0.49 0.0011
MAP (mmHg) 54 [51–59] 62 [60–66] 0.0001 65 [57–64] 69 [58–65] < 0.0001 0.006
DAP (mmHg) 43 [41–49] 50 [45–53] 0.0001 47 [43–51] 48 [41–52] 0.16 0.03
Stroke volume (ml) 60 [53–73] 72 [62–85] 0.0006 64 [55–92] 81 [67–97] < 0.0001 0.17
Cardiac output (l/min) 4.0 [3.3–4.6] 4.3 [3.5–5.7] 0.0005 4.6 [3.6–5.6] 5.4 [3.7–6.5] < 0.0001 0.10
PPV (%) 14 [11–19] 8 [7–11] 0.0001 10 [8–13] 8 [6–10] 0.0001 0.001
SVV (%) 16 [13–23] 14 [13–19] 0.0017 15 [12–21] 13 [10–16] 0.0006 0.46
Eadyn 0.75 [0.66–1.02] 0.57 [0.48–0.70] 0.0002 0.62 [0.48–0.82] 0.63 [0.39–0.82] 0.14 0.01
Ea (mmHg/ml)/SAP 1.06 [0.90–1.30] 1.06 [0.86–1.27] 0.34 1.06 [0.84–1.36] 0.88 [0.73–1.11] < 0.0001 0.96
Ea (mmHg/ml)/MAP 0.93 [0.69–1.1] 0.92 [0.70–0.97] 0.20 0.85 [0.67–1.12] 0.74 [0.60–1.00] < 0.0001 0.89
C (ml/mmHg) 2.15 [1.66–2.37] 2.02 [1.60–2.52] 0.30 2.09 [1.70–2.46] 2.38 [1.95–2.94] < 0.0001 0.91
R (mmHg/s/ml) 13.4 [10.5–18.0] 14.7 [9.6–20.1] 0.7 13.0 [10.9–16.5] 12.5 [9.4–17.0] 0.001 0.81
FTc (ms) 292 [266–306] 323 [298–334] 0.0002 317 [272–346] 331 [285–380] 0.0001 0.02
PV (cm/s) 66 [56–84] 66 [56–85] 0.03 75 [59–91] 76 [66–94] 0.005 0.30
  1. Values are expressed as median [percentile, 25–75]
  2. P1 difference between before and after VE in responders, P2 difference between before and after VE in non-responders, P3 difference between responders and non-responders before volume expansion, responders MAP increase ≥ 10% after volume expansion, C net arterial compliance, DAP diastolic arterial pressure, Ea effective arterial elastance, Eadyn dynamic arterial elastance, FTc corrected aortic flow time, MAP mean arterial pressure, VE volume expansion, NEO neosynephrine, PP arterial pulse pressure, PPV pulse pressure variations, PV peak velocity of aortic blood flow, R arterial resistance, SAP systolic arterial pressure, SVV stroke volume variations