Table 5 Hemodynamic variables before and after volume expansion in responder and non-responder patients
Responders (n = 21) | Non-responders (n = 35) | ||||||
|---|---|---|---|---|---|---|---|
Before VE | After VE | P1 | Before VE | After VE | P2 | P3 | |
Heart rate (bpm) | 62 [58–72] | 60 [54–71] | 0.0028 | 65 [57–74] | 60 [56–71] | < 0.0001 | 0.71 |
SAP (mmHg) | 77 [66–80] | 86 [79–93] | 0.0001 | 82 [79–87] | 80 [77–86] | 0.49 | 0.0011 |
MAP (mmHg) | 54 [51–59] | 62 [60–66] | 0.0001 | 65 [57–64] | 69 [58–65] | < 0.0001 | 0.006 |
DAP (mmHg) | 43 [41–49] | 50 [45–53] | 0.0001 | 47 [43–51] | 48 [41–52] | 0.16 | 0.03 |
Stroke volume (ml) | 60 [53–73] | 72 [62–85] | 0.0006 | 64 [55–92] | 81 [67–97] | < 0.0001 | 0.17 |
Cardiac output (l/min) | 4.0 [3.3–4.6] | 4.3 [3.5–5.7] | 0.0005 | 4.6 [3.6–5.6] | 5.4 [3.7–6.5] | < 0.0001 | 0.10 |
PPV (%) | 14 [11–19] | 8 [7–11] | 0.0001 | 10 [8–13] | 8 [6–10] | 0.0001 | 0.001 |
SVV (%) | 16 [13–23] | 14 [13–19] | 0.0017 | 15 [12–21] | 13 [10–16] | 0.0006 | 0.46 |
Eadyn | 0.75 [0.66–1.02] | 0.57 [0.48–0.70] | 0.0002 | 0.62 [0.48–0.82] | 0.63 [0.39–0.82] | 0.14 | 0.01 |
Ea (mmHg/ml)/SAP | 1.06 [0.90–1.30] | 1.06 [0.86–1.27] | 0.34 | 1.06 [0.84–1.36] | 0.88 [0.73–1.11] | < 0.0001 | 0.96 |
Ea (mmHg/ml)/MAP | 0.93 [0.69–1.1] | 0.92 [0.70–0.97] | 0.20 | 0.85 [0.67–1.12] | 0.74 [0.60–1.00] | < 0.0001 | 0.89 |
C (ml/mmHg) | 2.15 [1.66–2.37] | 2.02 [1.60–2.52] | 0.30 | 2.09 [1.70–2.46] | 2.38 [1.95–2.94] | < 0.0001 | 0.91 |
R (mmHg/s/ml) | 13.4 [10.5–18.0] | 14.7 [9.6–20.1] | 0.7 | 13.0 [10.9–16.5] | 12.5 [9.4–17.0] | 0.001 | 0.81 |
FTc (ms) | 292 [266–306] | 323 [298–334] | 0.0002 | 317 [272–346] | 331 [285–380] | 0.0001 | 0.02 |
PV (cm/s) | 66 [56–84] | 66 [56–85] | 0.03 | 75 [59–91] | 76 [66–94] | 0.005 | 0.30 |