Respiratory variations of inferior vena cava fail to predict fluid responsiveness in mechanically ventilated patients with isolated left ventricular dysfunction

Annals of Intensive Care

Table 3 dIVC for the detecting of fluid responsiveness

Categories	AUC	95% CI	p	Optimum cutoff (%)	Sen (%)	Spe (%)	PPV (%)	NPV (%)
All patients (n = 129)	0.815	0.742–0.889	< 0.001	16.5	79.0	72.1	72.4	78.7
NLVF (n = 101)^a	0.918	0.858–0.978	< 0.001	14.5	82.7	87.0	89.7	84.5
ILVD (n = 28)	0.550	0.283–0.817	0.729	21.5	40.0	58.3	17.3	81.7

NLVF normal left ventricular function, ILVD isolated left ventricular systolic dysfunction, dIVC inferior vena cava distensibility index, AUC area-under-the-curve, CI confidence interval, Sen sensitivity, Spe specificity, PPV positive predictive value, NPV negative predictive value
^aIn comparison with AUC derived from all patients, p = 0.033