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Table 3 Prediction and identification of fluid responsiveness: least significant change (LSC), timing and proposed cut off value of changes in cardiac index (CI), stroke volume index (SVI), pulse pressure variation (PPV) and stroke volume variation (SVV)

From: Evaluation of least significant changes of pulse contour analysis-derived parameters

Tests to predict fluid responsiveness
Tests Variable Timing (s) Cut off LSC
Occlusion test CI 15/30 5% 1.2% (0.2–5.0)
MiniFluid SVI 60 6% 1.3% (0–4.2)
PPV 60 2% (absolute change) 8.9% (0–26%)
SVV 60 2% (absolute change) 7.5% (0–35%)
Passive leg raising CI 90 10–15% 1.3% (0.5–5.6)
Tidal volume challenge PPV 60 3.5% (absolute change) 8.9% (0–26%)
SVV 60 2.5% (absolute change) 7.5% (0–35%)
Identification of fluid responsiveness
Variable Timing (min) Cut off (%) LSC
SVI 10 10–15 0.5% (0.2–3.5)
SVI 15 10–15 0.5% (0.2–3.4)
CI 10 10–15 0.7% (0.4–4.1)
CI 15 10–15 0.7% (0.3–3.3%)
  1. Results for LSC are median (5–95th percentiles)