Table 1 Baseline patient demographic and clinical characteristics (n = 12)
Variables | N = 12 |
|---|---|
Age, years | 74.0 ± 11.0 |
Male gender, n (%) | 9 (75%) |
Body mass index, kg/m2 | 22 ± 3 |
Long-term oxygen therapy, n (%) | 3 (25%) |
Comorbidity, n (%) | |
Diabetes mellitus | 2 (17%) |
Hypertension | 8 (67%) |
Coronary artery disease | 3 (25%) |
Chronic kidney disease | 4 (33%) |
Others | 2 (17%) |
Post-bronchodilator FEV1/FVC, % | 45 [35–55] |
Post-bronchodilator FEV1, % predicted | 34 [31–47] |
APACHE II at enrollment | 12 ± 4 |
Arterial blood gas at enrollment | |
pH | 7.36 [7.28–7.37] |
PaCO2, mmHg | 51 [42–60] |
PaO2, mmHg | 139 [80–233] |
Time from initiation of NIV to enrollment, hours | 17 [5–68] |
Non-invasive ventilation setting at enrollment | |
Inspiratory positive airway pressure, cmH2O | 11 [10–12] |
Expiratory positive airway pressure, cmH2O | 5 [5] |
Tidal volume, mL | 425 [370–514] |
Oxygen flow rate, liters per minute | 4 [3–5] |