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Table 3 Multivariate analysis of the different VD/VT estimates and VR at days 1 and 2 (N = 635)

From: Estimated dead space fraction and the ventilatory ratio are associated with mortality in early ARDS

VariableDay 1Day 2
OR (95% CI)p-valueOR (95% CI)p-value
VD/VT
 Harris–Benedict1.13 (0.93–1.37)0.201.15 (0.96–1.38)0.11
 Penn State1.17 (0.96–1.44)0.111.21 (0.98–1.50)0.06
 Direct1.20 (0.97–1.48)0.091.28 (1.02–1.61)0.03
VR1.13 (0.97–1.32)0.101.20 (1.01–1.40)0.03
  1. Corrected for the following co-variates: APACHE IV, PEEP, PaO2/FiO2, driving pressure and compliance of the respiratory system
  2. VD/VT estimated dead space fraction, VR ventilatory ratio