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Table 3 Risk factors for 90-day mortality in the overall population (patients where BAL was performed, n = 85)

From: Outcome and prognostic factors of Pneumocystis jirovecii pneumonia in immunocompromised adults: a prospective observational study

  Univariate analysis (n = 85) Multivariate analysis (n = 85)
OR 95% CI p value OR 95% CI p value
Characteristics
 Age > 55 years 1.24 1.02–1.5 < 0.05 1.02 0.82–1.2 0.87
 BMI 1 0.97–1.02 0.94    
 Serum albumin, g/L 0.99 0.97–1.01 0.4    
 Glucocorticoid treatment 1.15 0.95–1.4 0.16    
 HIV infection 0.74 0.52–0.95 0.02 0.8 0.82–1.2 0.87
Bronchoalveolar lavage (BAL)
 Alveolitis profile of BAL 0.75 0.61–0.92 0.007 0.79 0.65–0.96 0.02
 Neutrophils 1.02 0.99–1.04 0.12    
 Macrophages 1.01 0.99–1.04 0.21
 Lymphocytes 0.97 0.94–0.99 0.06
Co-infection
 Bacterial 1.2 0.95–1.6 0.13    
 Viral 1.25 1.02–1.52 0.03 1.2 0.99–1.4 0.07
 Invasive fungal 1.21 0.76–1.9 0.41    
Blood tests
 White blood cell counts 1 0.99–1 0.69    
 Polynuclear neutrophils 1.07 0.8–1.4 0.76    
 Lymphocytes 0.95 0.8–1.4 0.62    
 Serum CRP 1 0.99–1 0.24    
Severity
 SAPS2 1 1–1.01 0.008    
 SOFA score 1.08 1.05–1.1 < 0.0001 1.05 1.02–1.09 0.0002
 Severe SDRA 1.38 1.14–1.7 < 0.0001    
 P/F ratio > 200 0.78 0.64–0.96 < 0.05    
  1. Italics characters correspond to the analysis parameters with a statistically significant difference
  2. BMI, body mass index; SAPS2, simplified acute physiology score version 2, SOFA score, sequential organ failure assessment score; HIV, human immunodeficiency virus