Skip to main content

Table 3 Risk factors for 90-day mortality in the overall population (patients where BAL was performed, n = 85)

From: Outcome and prognostic factors of Pneumocystis jirovecii pneumonia in immunocompromised adults: a prospective observational study

 

Univariate analysis (n = 85)

Multivariate analysis (n = 85)

OR

95% CI

p value

OR

95% CI

p value

Characteristics

 Age > 55 years

1.24

1.02–1.5

< 0.05

1.02

0.82–1.2

0.87

 BMI

1

0.97–1.02

0.94

   

 Serum albumin, g/L

0.99

0.97–1.01

0.4

   

 Glucocorticoid treatment

1.15

0.95–1.4

0.16

   

 HIV infection

0.74

0.52–0.95

0.02

0.8

0.82–1.2

0.87

Bronchoalveolar lavage (BAL)

 Alveolitis profile of BAL

0.75

0.61–0.92

0.007

0.79

0.65–0.96

0.02

 Neutrophils

1.02

0.99–1.04

0.12

   

 Macrophages

1.01

0.99–1.04

0.21

 Lymphocytes

0.97

0.94–0.99

0.06

Co-infection

 Bacterial

1.2

0.95–1.6

0.13

   

 Viral

1.25

1.02–1.52

0.03

1.2

0.99–1.4

0.07

 Invasive fungal

1.21

0.76–1.9

0.41

   

Blood tests

 White blood cell counts

1

0.99–1

0.69

   

 Polynuclear neutrophils

1.07

0.8–1.4

0.76

   

 Lymphocytes

0.95

0.8–1.4

0.62

   

 Serum CRP

1

0.99–1

0.24

   

Severity

 SAPS2

1

1–1.01

0.008

   

 SOFA score

1.08

1.05–1.1

< 0.0001

1.05

1.02–1.09

0.0002

 Severe SDRA

1.38

1.14–1.7

< 0.0001

   

 P/F ratio > 200

0.78

0.64–0.96

< 0.05

   
  1. Italics characters correspond to the analysis parameters with a statistically significant difference
  2. BMI, body mass index; SAPS2, simplified acute physiology score version 2, SOFA score, sequential organ failure assessment score; HIV, human immunodeficiency virus