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Table 1 Patients’ demographic and clinical characteristics at admission

From: Epidemiology, clinical features, and management of severe hypercalcemia in critically ill patients

 

All

(n = 131)

Hemopathy

(n = 58)

Solid tumors

(n = 29)

Endocrinopathies (n = 16)

Other (n = 28)

Clinical data

 Age (y)

58.5 [48.5; 69]

58 [42; 67]

63 [52; 68]

52 [36.5; 67.25]

66 [55.25; 74.25]

 Women, n (%)

64 (48.8)

22 (38)

17 (58.6)

9 (56)

16 (57.1)

 Chronic kidney disease, n (%)

25 (19.5)

10 (17.2)

2 (6.8)

4 (25)

10 (35.7)

 Cardiopathy, n (%)

32 (25)

8 (13.7)

6 (20.7)

4 (25)

15 (53.5)

 SOFA score at day 1

2 [1, 4]

4 [2, 5]

1 [1, 3]

1 [0; 2]

2 [1, 3]

 SAPS II score at day 1

29.5 [22; 36.75]

34 [28, 40]

33 [24, 37]

19.5 [16.75; 29.25]

27 [18.5; 33]

 ECOG/WHO scale score

1 [0; 3]

1 [0; 2]

3 [1, 3]

0.5 [0; 2.75]

1 [0; 3]

 Charlson score

4 [2, 6]

3 [2, 4]

7 [6, 9]

3 [1, 6]

4 [2; 6.25]

Admission diagnosis in ICU

 Hypercalcemia, n (%)

101 (77.1)

42 (72.4)

22 (76)

13 (81)

23 (82)

 Coma, delirium, n (%)

9 (6.8)

3 (5.2)

5 (17.2)

0

1 (3.5)

 Acute respiratory failure, n (%)

5 (3.8)

4 (6.8)

1 (3.4)

0

0

 Tumor lysis syndrome, n (%)

4 (3)

4 (6.8)

0

0

0

 Acute kidney injury, n (%)

4 (3)

2 (3.4)

1 (3.4)

0

1 (3.5)

 Sepsis, n (%)

5 (3.8)

1 (1.7)

0

3 (19)

1 (3.5)

 Other, n (%)

3 (2.2)

2 (3.4)

0

0

2 (7)

  1. Values for categorical variables are given as number (percentage); values for continuous variables, as median [interquartile range]
  2. Other causes included iatrogenic causes (n = 16; 57.1%), sarcoidosis (n = 4; 14.2%), tuberculosis (n = 1; 3.5%), atypical mycobacterial infection (n = 1; 3.5%), global dehydration (n = 1; 3.5%), and unknown causes (n = 5; 17.8%)
  3. ECOG/WHO Eastern Cooperative Oncology Group/World Health Organization, SAPS II Simplified Acute Physiology Score, SOFA Sequential Organ Failure Assessment