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Table 2 Characteristics of AKI

From: Epidemiology, clinical features, and management of severe hypercalcemia in critically ill patients

Variable

Value

Scr (mg/dL) 3 months before ICU admission

0.9 [0.7; 1.2]

eGFR (mL/min/1.73 m2) before ICU admission

85 [63; 109]

Polyuria, n (%)

15 (11.4)

AKI, n (%)

108 (82.4)

AKI stage

 Stage 1, n (%)

37 (34.2)

 Stage 2, n (%)

30 (27.7)

 Stage 3, n (%)

41 (37.9)

Scr (mg/dL) at ICU admission

1.88 [1.1; 3.2]

Scr (mg/dL) at day 3

1.5 [0.9; 2.7]

Scr (mg/dL) at day 5

1.4 [0.9; 2.5]

Scr (mg/dL) at day 7

1.3 [0.8; 2.3]

Maximal Scr (mg/dL)

1.95 [1.1; 3.4]

Scr (mg/dL) at ICU discharge

1 [0.7; 1.7]

RRT during ICU stay

25 (19%)

Duration of RRT (d)

5 [2.5; 7]

Causes of AKI

 Hypoperfusion

68 (63%)

 Acute tubular necrosis

20 (19%)

 Cast nephropathy

18 (16%)

 Obstructive

11 (10%)

 Tumor lysis syndrome

8 (7%)

 Sarcoidosis

3 (3%)

 Nephrotoxic agents

2 (2%)

 Kidney infiltration by malignancy

1 (1%)

 Amyloidosis

1 (1%)

 > 1 cause

30 (23%)

Follow-up data

 Scr (mg/dL) at month 3 in RRT-free patients

0.9 [0.7; 1.3]

 eGFR (mL/min/1.73 m2) at month 3 in RRT-free patients

86 [63; 109]

 Scr (mg/dL) at month 6 in RRT-free patients

0.9 [0.7; 1.3]

 eGFR (mL/min/1.73 m2) at month 6 in RRT-free patients

77 [54; 96]

  1. n = 131. Percentages values are given based for the 108 patients who presented AKI. Values of categorical variables are given as number (percentage); values for continuous variables, as median [interquartile range]. Conversion factor for Scr in mg/dL to µmol/L is 88.4
  2. AKI acute kidney injury, eGFR estimated glomerular filtration rate based on MDRD formula, ICU intensive-care unit, RRT renal replacement therapy, Scr serum creatinine
  3. Conversion factor: Scr, serum creatinine in mg/dL to µmol/L, ×88.4