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Table 3 Univariable logistic regression analyzing risk factor for infection due to multidrug-resistant Gram-negative bacteria

From: Gastrointestinal colonization with multidrug-resistant Gram-negative bacteria during extracorporeal membrane oxygenation: effect on the risk of subsequent infections and impact on patient outcome

Clinical characteristicsInfected (n = 37)Non-infected (n = 54)pOdds ratioa (95% CI)
Year
 20105 (14%)8 (15%)0.970 
 20116 (16%)8 (15%)  
 20124 (11%)9 (17%)  
 20136 (16%)9 (17%)  
 20148 (22%)11 (20%)  
 20158 (22%)9 (17%)  
Age (years)50 (37–55)47 (36–58)0.5871.00 (0.98–1.03)
Gender (male)28 (76%)29 (54%)0.0302.68 (1.09–7.00)
Charlson Comorbidity Index1 (0–3)1 (0–3)0.8391.21 (0.17–7.82)
Transferred from peripheral hospital32 (86%)43 (80%)0.3931.63 (0.53–5.62)
IMV > 3 days prior to ECMO connection22 (59%)9 (17%)0.0017.33 (2.86–20.3)
RRT prior to ECMO connection11 (30%)4 (7%)0.0055.29 (1.63–20.6)
SOFA8 (6–12)8 (6–11)0.3481.05 (0.94–1.17)
SAPS II38 (32–49)37 (30–43)0.8061.00 (0.97–1.03)
ARDS35 (95%)37 (69%)0.0018.04 (2.09–53.0)
PaO2/FiO2 < 100 mmHg32 (86%)38 (70%)0.0662.69 (0.93–8.97)
Infection at admission31 (84%)33 (61%)0.0173.28 (1.22–9.93)
Chronic immunosuppressionb8 (78%)12 (78%)0.9460.96 (0.34–2.63)
Veno-venous support34 (92%)45 (83%)0.2232.26 (0.62–10.8)
Colonization16 (43%)3 (6%)0.00112.9 (3.83–59.9)
  1. Data are presented as absolute frequency (% of the included patients) or as median and interquartile range
  2. IMV invasive mechanical ventilation, ECMO extracorporeal membrane oxygenation, RRT renal replacement therapy, SOFA sequential organ failure assessment, SAPS II simplified acute physiology score, ARDS acute respiratory distress syndrome, ICU intensive care unit, LOS length of stay
  3. aOdds ratio of continuous variables are odds ratio per unit increase in variable
  4. bIncluding high-dosage corticosteroids, immunosuppressants or both. Statistically significant results are highlighted in italic