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Table 3 SP-D polymorphisms in sepsis patients according to AKI KDIGO stage

From: Surfactant protein D (SP-D) gene polymorphism rs721917 is an independent predictor of acute kidney injury development in sepsis patients: a prospective cohort study

SP-D polymorphisms

AKI KDIGO stages

P

1

2

3

N

N = 46

N = 78

N = 32

rs721917 genotypes

 CC

7 (15)

31 (40)

16 (50)

0.003**

 CT

29 (63)

32 (41)

12 (38)

0.030*

 TT

10 (22)

15 (19)

4 (12)

0.577

rs721917 alleles

 C

43 (47)

94 (60)

44 (69)

0.017*

 T

49 (53)

62 (40)

20 (31)

 

rs2243639 genotypes

 AA

7 (15)

12 (15)

6 (19)

0.895

 AG

16 (35)

33 (42)

12 (38)

0.694

 GG

23 (50)

33 (42)

14 (42)

0.700

rs2243639 alleles

 A

30 (33)

57 (37)

24 (38)

0.771

 G

62 (67)

99 (63)

40 (62)

 
  1. * Compared with TT genotype, P < 0.05
  2. ** Compared with TT genotype, P < 0.01