Variable | Cutoff value for considering an insufficient response |
---|---|
Mean arterial pressure | < 65 mm Hg |
Heart rate | > 120 beats/min |
Central venous pressure | > 6 mm Hg |
Lactate clearance | < 20%/2-h |
Central venous O2 saturation | < 70% |
Central venous–arterial PCO2 difference | > 6 mm Hg |
Urine output | < 0.5 mL/kg/h |
Capillary-refill time | > 3.0 s |
Skin mottling | Present |