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Table 2 Characteristics of intermittent hemodialysis sessions

From: Bedside prediction of intradialytic hemodynamic instability in critically ill patients: the SOCRATE study

 AllFirstLaterP
Number of sessions21172139 
Number of days since ICU admission8 [3–12]3 [2–5]10 [7–15]< 0.0001
SOFA score (without renal points)6 [2–11]8 [4–13]4 [1–9]0.0001
Organ support therapy at T0
Invasive mechanical ventilation130 (62%)48 (67%)82 (59%)0.30
Vasopressors90 (43%)44 (61%)46 (30%)0.0001
Norepinephrine80 (38%)36 (50%)44 (32%) 
Epinephrine10 (5%)8 (11%)2 (1%) 
Cardiovascular SOFA score ≥ 1 at T0104 (49%)48 (67%)56 (40%)0.0003
Tissue perfusion parameters at T0
Lactate > 2 mmol/L49 (23%)33 (46%)16 (12%)< 0.0001
Index capillary refill time ≥ 3 s38 (18%)23 (32%)15 (11%)0.0003
Hemodialysis settings
Duration (hours)4 [4–4]4 [4–4]4 [4–5]0.015
Ultrafiltration135 (64%)25 (35%)110 (79%)< 0.0001
Volume of ultrafiltration (L)2.5 [2.0–3.0]2.0 [1.6–3.0]2.6 [2.0–3.1]0.10
Intradialytic hemodynamic instability48 (23%)31 (43%)17 (12%)< 0.0001
Timing of first hemodynamic instability   0.092
Before first hour35 (73%)24 (77%)4 (24%) 
Between first and second hour6 (13%)3 (10%)1 (6%) 
Between second and fourth hour7 (14%)4 (13%)3 (18%) 
Therapeutic interventions (not exclusive)
Increase in vasopressors35 (73%)24 (77%)11 (65%) 
Fluid administration15 (31%)13 (42%)2 (12%) 
Initiation of vasopressors7 (15%)5 (16%)2 (12%) 
Decrease in ultrafiltration3 (6%)03 (18%) 
Cessation of ultrafiltration3 (6%)03 (18%) 
  1. Quantitative variables are expressed as median [25–75th percentiles] and qualitative variables as number (%)