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Table 2 Multivariate analysis for explaining early intubation

From: Use, timing and factors associated with tracheal intubation in septic shock: a prospective multicentric observational study

 Odds ratio [95% confidence interval]P-value% of r2 contributionCovariate rank in r2 contribution
Use of accessory respiratory musclesa5.63 [2.83–11.82]< 0.00112.83
pH (for each 0.1 decrease)a1.51 [1.09–2.97]0.023.87
Glasgow score (reference ≥ 14)a  39.51
10–13 vs ≥ 143.03 [1.20–7.63]0.01  
<10 vs ≥ 1439.95 [10.13–134.85]< 0.001  
Inability to clear tracheal secretionsa2.64 [1.38–3.96]0.026.026
Vasopressor (for each 1 μg/kg/min increase)a2.34 [1.38–3.96]0.0015.75
Lactate (for each 1 mmol/L increase)a1.11 [1.01–1.21]0.028.64
 Variance estimate [95% confidence interval]   
Variable effect: center0.50 [0.12–1.81]< 0.0116.32
  1. Overall r2 of the model was 0.6
  2. Parameters entered in the model not presented in the table, with a P-value > 0.1: age, sex, weight, NYHA status, chronic respiratory failure, chronic renal failure, immunosuppression, pulmonary and urinary site of infection, pathogen, respiratory rate, PaCO2, PaO2/FiO2 ratio, fluid loading from first hypotension to H0
  3. aWorst value recorded between H0 and H8, or between H0 and immediately before intubation if performed before H8