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Table 1 Baseline characteristics and their univariate association with 1-year survival tested by Cox proportional hazard model

From: One-year survival in acute stroke patients requiring mechanical ventilation: a multicenter cohort study

Variable
N (%) or median [Q1; Q3]
All
N = 419
1-year survival
Alive
N = 114
Dead
N = 305
HR (95% CI)p
Demographics/history
 Age, years68.2 [57.9; 76.3]67.2 [57.4; 74.8]69.1 [58.4; 76.9]1.00 (0.99; 1.00)0.35
 Male sex251 (59.9)66 (57.9)185 (60.7)1.01 (0.81; 1.27)0.93
 Hypertension238 (57.3)72 (63.2)166 (55.1)1.20 (0.95; 1.52)0.12
 Diabetes mellitus81 (19.3)21 (18.4)60 (19.7)1.05 (0.79; 1.39)0.72
 Atrial fibrillation/flutter55 (13.3)13 (11.4)42 (14)0.86 (0.63; 1.19)0.38
 BMI ≥ 30 kg/m262 (15.3)15 (13.5)47 (16)0.91 (0.67; 1.25)0.57
 Charlson comorbidity index ≥ 1215 (51.3)63 (55.3)152 (49.8)1.16 (0.93; 1.45)0.20
Stroke characteristics
 Stroke type
  Ischemic191 (45.6)66 (57.9)125 (41)Ref< .01
  Hemorrhagic178 (42.5)35 (30.7)143 (46.9)0.58 (0.45; 0.74).
  SAH50 (11.9)13 (11.4)37 (12.1)0.59 (0.41; 0.85).
  Acute-phase stroke therapy70 (16.7)33 (28.9)37 (12.1)1.96 (1.39; 2.78)< .01
  Time from stroke to ICU admission, days1 [1, 2]1.5 [1, 5]1 [1, 2]1.05 (1.02; 1.09)< .01
ICU admission
 Period of admission
  1996–200234 (8.1)9 (7.9)25 (8.2)Ref0.55
  2003–2009228 (54.4)64 (56.1)164 (53.8)0.83 (0.54; 1.25).
  2010–2016157 (37.5)41 (36)116 (38)0.79 (0.51; 1.2).
 Type of ICU admission
  Transfer from ward150 (35.8)56 (49.1)94 (30.8)Ref< .01
  Direct (from ED or home)269 (64.2)58 (50.9)211 (69.2)0.63 (0.5; 0.81).
 Reason for intubation
  Elective procedure12 (2.9)10 (8.8)2 (0.7)Ref< .01
  Altered mental status302 (72.1)66 (57.9)236 (77.4)0.12 (0.03; 0.47).
  Respiratory failure52 (12.4)19 (16.7)33 (10.8)0.19 (0.05; 0.79).
  Seizure34 (8.1)19 (16.7)15 (4.9)0.30 (0.07; 1.33).
  Cardiac arrest19 (4.5)0 (0)19 (6.2)0.04 (0.01; 0.17).
 GCS at admission
  8–15110 (26.3)57 (50)53 (17.4)Ref< .01
  3–7309 (73.7)57 (50)252 (82.6)0.36 (0.27; 0.49).
  SAPS 258 [47; 72]46.5 [39; 58]62 [53; 75]0.95 (0.95; 0.96)< .01
  Non-neurologic SOFA4 [1, 6]3 [1, 6]4 [2, 6]1.03 (0.99; 1.07)0.14
  1. HR, hazard ratio; CI, confidence interval; BMI, body max index; SAH, subarachnoid hemorrhage; ICU, intensive care unit; ED, emergency department; GCS, Glasgow coma scale; SAPS, simplified acute physiology score; SOFA, Sequential Organ Failure Assessment