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Table 2 Patients characteristics and outcomes, according to stroke subtype

From: One-year survival in acute stroke patients requiring mechanical ventilation: a multicenter cohort study

Variable
N (%) or median [Q1; Q3]
AIS
n = 191
ICH
n = 178
SAH
n = 50
p
Demographics/history
 Age, years69.4 [61.1; 76.5]67.7 [57.7; 76]62.5 [54.3; 76]0.10
 Male sex129 (67.5)105 (59)17 (34)<.01
 Charlson comorbidity index ≥ 1115 (60.2)85 (47.8)15 (30)<.01
 Period of admission   0.67
  1996–200218 (9.4)12 (6.7)4 (8).
  2003–2009108 (56.5)95 (53.4)25 (50).
  2010–201665 (34)71 (39.9)21 (42).
Stroke characteristics
 AIS location
  Anterior circulation117 (61.6) 
  Posterior circulation69 (36.3) 
 ICH location   
  Lobar76 (45.5) 
  Deep50 (29.9) 
  Infratentorial21 (24.6) 
  Acute-phase stroke therapya39 (20.4)16 (9)19 (38)< .01
  Intravenous thrombolysis17 (8.9) 
  Intra-arterial thrombolysis10 (5.2) 
  Endovascular thrombectomy8 (4.2) 
  Craniectomy4 (2.1)1 (0.6)0 
  External ventricular drainage9 (5.1)7 (14) 
  Surgical hematoma evacuation6 (3.4)1 (2) 
  Aneurysm surgical clipping2 (1.12)1 (2) 
  Aneurysm endovascular coiling05 (10) 
  Time from stroke to ICU admission, days2 [1, 4]1 [1]1 [1]< .01
ICU admission
 Type of ICU admission   < .01
  Direct (from ED or home)89 (46.6)137 (77)43 (86).
  Transfer from ward102 (53.4)41 (23)7 (14).
 Reason for intubation   < .01
  Altered mental status116 (60.7)154 (86.5)32 (64).
  Respiratory failure46 (24.1)6 (3.4)0 (0).
  Seizure19 (9.9)11 (6.2)4 (8).
  Cardiac arrest5 (2.6)5 (2.8)9 (18) 
  Elective procedure5 (2.6)2 (1.1)5 (10).
  GCS at admission6 [3, 10]3 [3, 6]3 [3, 7]< .01
  GCS < 8120 (62.8)151 (84.8)38 (76) 
  SAPS 256 [45; 67]61 [51; 77]59.5 [50; 72]< .01
  Non-neurologic SOFA4 [2, 7]4 [1, 5]3 [2, 6]0.14
ICU stay
 Duration of mechanical ventilation, days5 [3, 12]3 [2, 8]3 [1, 6]< .01
 Vasopressor support92 (48.2)78 (43.8)28 (56)0.30
 Renal replacement therapy17 (8.9)4 (2.2)6 (12)< .01
 Withdrawal/withholding of care77 (40.3)66 (37.1)15 (30)0.40
 ICU length of stay, days7 [4, 15]3 [2, 9]3.5 [2, 8]< .01
 Hospital length of stay, daysb15 [6, 35]5 [2, 15]4 [2, 16]< .01
Survival rates
 ICU survival89 (46.6)50 (28.1)18 (36)< .01
 Hospital survival71 (37.2)43 (24.2)15 (30)0.03
 1-year survivalc54 (30.2)30 (17.3)5 (11.9)< .01
  1. AIS, acute ischemic stroke; ICH, intracranial hemorrhage; SAH, subarachnoid hemorrhage; ICU, intensive care unit; ED, Emergency Department; GCS, Glasgow coma scale; SAPS, simplified acute physiology score; SOFA, Sequential Organ Failure Assessment
  2. aA single patient could benefit from more than one type of acute-phase stroke therapy
  3. b8 missing data
  4. c25 missing data