Skip to main content

Table 1 Characteristics of the patients who succeed the spontaneous breathing trial (SBT)

From: Thenar oxygen saturation (StO2) alterations during a spontaneous breathing trial predict extubation failure

 

Extubation success (n = 147)

Extubation failure (n = 23)

Age (years)

66 ± 14

67 ± 12

Days on MV (n)

7 ± 5

8 ± 6

Pre-existent comorbidities (%)

 Diabetes mellitus

33

35

 Hypertension

57

48

 Cardiac disease

23

22

 COPD

16

30

Etiology of acute respiratory failure (%)

 Septic shock

29

26

 Heart failure

17

26

 Respiratory

20

26

 Trauma

6

0

 Other

29

22

 

Baseline

Minute 30

Baseline

Minute 30

HR (beats/min)

88 ± 16

91 ± 16

83 ± 17

87 ± 18

MAP (mmHg)

82 ± 13

85 ± 15

79 ± 14

80 ± 12

RR (resp/min)

19 ± 4

23 ± 5

18 ± 3

23 ± 4

Vt (mL)

454 ± 96

430 ± 123

438 ± 115

367 ± 132

pH

7.46 ± 0.05

7.44 ± 0.06

7.47 ± 0.04

7.44 ± 0.04

pCO2 (mmHg)

37 ± 6

38 ± 6

41 ± 9

42 ± 14 †

Hb (g/dL)

9.9 ± 1.8

9.9 ± 1.8

10.1 ± 2

10.3 ± 2.1

SaO2 (%)

96 ± 8

97 ± 3

97 ± 3

96 ± 3

ScvO2 (%)

66 ± 9

66 ± 8

62 ± 9

61 ± 5*

StO2 (%)

80 ± 6

80 ± 7

76 ± 11

77 ± 9

DeO2 (%/min)

− 13.1 ± 8.4

− 13.6 ± 10.7

− 12.7 ± 7

− 17.2 ± 10.3

nirVO2 (U)

139 ± 80

159 ± 135

129 ± 75

174 ± 97

THI (U)

10.7 ± 2.9

11.3 ± 3.1

10.0 ± 3.9

10.5 ± 4.0

ReO2 (%/s)

4.1 ± 1.6

4.2 ± 1.8

3.3 ± 1.9*

3.7 ± 2.0

Hyperemia AUC (U)

12.2 ± 6.5

12.9 ± 5.7

7.1 ± 4.7**

8.4 ± 4.1**

DeO2 ratio

 

1.1 ± 0.3

 

1.5 ± 0.6**

nirVO2 ratio

 

1.1 ± 0.4

 

1.5 ± 0.5*

  1. MV Mechanical ventilation, COPD Chronic obstructive pulmonary disease, HR heart rate, MAP mean arterial pressure, RR respiratory rate, Vt tidal volume, pCO2 arterial partial pressure of carbon dioxide, Hb Hemoglobin, SaO2 arterial oxygen saturation, ScvO2 central venous oxygen saturation, StO2 tissue oxygen saturation, DeO2 StO2 deoxygenation rate, nirVO2 NIRS-derived local oxygen consumption, THI tissue hemoglobin index, ReO2 StO2 reoxygenation rate
  2. * p < 0.05; and ** p < 0.01, as compared to success group at the same time point; p < 0.05, as compared to baseline values within the group