Skip to main content

Table 1 Comparison of acute patients admitted for sepsis versus acute patients admitted for other reason

From: Sepsis at ICU admission does not decrease 30-day survival in very old patients: a post-hoc analysis of the VIP1 multinational cohort study

Admission category

All acute patients

Other categories

Sepsis

p value

N (%)

3869 (100%)

3376 (87.3%)

493 (12.7%)

 

Age (years)a

84 (82–86)

84 (82–87)

83 (81–86)

< 0.0001

Gender (male)

2013 (52%)

1748 (51.8%)

265 (53.8%)

0.4402

Hospital LOS before ICU (days)a

1 (0–3)

1 (0–3)

1 (0–3)

0.4600

SOFA score at admissiona

8 (5–11)

7 (5–11)

9 (6–12)

< 0.0001

ICU LOS (days)a

2.96 (1.17–6.81)

2.88 (1.12–6.67)

3.54 (1.5–8)

0.0036

Frailty (CFS)

 Fit (CFS 1–3)

1331 (34.4%)

1166 (34.5%)

165 (33.5%)

0.0737

 Vulnerable (CFS 4)

719 (18.6%)

643 (19%)

76 (15.4%)

 

 Frail (CFS 5–9)

1819 (47%)

1567 (46.4%)

252 (51.1%)

 

 Fit or vulnerable

2050 (53%)

1809 (53.6%)

241 (48.9%)

0.0568

Frail

1819 (47%)

1567 (46.4%)

252 (51.1%)

Interventions in ICU

 At least 1 intervention

3196 (82.6%)

2760 (81.8%)

436 (88.4%)

0.0003

 No interventions

673 (17.4%)

616 (18.2%)

57 (11.6%)

 Mechanical ventilation

2087 (53.9%)

1853 (54.9%)

234 (47.5%)

0.0024

 Non-invasive ventilation

1047 (27.1%)

939 (27.8%)

108 (21.9%)

0.0069

 Vasoactive drugs

2265 (58.5%)

1860 (55.1%)

405 (82.2%)

< 0.0001

 RRT

421 (10.9%)

335 (9.9%)

86 (17.4%)

< 0.0001

Life-sustaining treatment limitations

 No LST limitations

2601 (67.2%)

2292 (67.9%)

309 (62.7%)

0.0243

 LST limitations

1268 (32.8%)

1084 (32.1%)

184 (37.3%)

 Withholding

679 (17.5%)

571 (16.9%)

108 (21.9%)

0.0196

 Withdrawing ± withholding

589 (15.2%)

513 (15.2%)

76 (15.4%)

 

Outcome

 ICU mortality

1072 (27.7%)

918 (27.2%)

154 (31.2%)

0.0686

 30-day mortality

1577 (40.8%)

1357 (40.2%)

220 (44.6%)

0.0687

  1. LOS length of stay, SOFA Sequential Organ Failure Assessment, CFS Clinical Frailty Scale, RRT renal replacement therapy, LST Life-sustaining treatment
  2. aExpressed as median, IQR
  3. No missing values except for length of ICU stay; 2 patients had a missing date of discharge