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Table 2 Factors affecting 30-day survival of ICU patients aged ≥ 80 years with SOFA ≥ 2 at admission, multivariate analysis

From: Sepsis at ICU admission does not decrease 30-day survival in very old patients: a post-hoc analysis of the VIP1 multinational cohort study

 

HR (95% CI)

p value

A. Results of the Cox analysis considering all acutely admitted patients (n = 3869)

 Sepsis

0.99 (0.86–1.15)

p = 0.9173

 Age (per 5-year increase)

1.16 (1.09–1.25)

p < 0.0001

 Frailty: vulnerable vs. fit

1.16 (1–1.35)

p = 0.0556

 Frailty: frail vs. fit

1.47 (1.31–1.66)

p < 0.0001

 Male vs. female

1.16 (1.05–1.28)

p = 0.0043

 SOFA score (per one-point increase)

1.13 (1.12–1.14)

p < 0.0001

B. Results of the Cox analysis considering only acute patients admitted for sepsis (n = 493)

 Age (per 5-year increase)

1.33 (1.1–1.61)

p = 0.0029

 Frailty: vulnerable vs. fit

1.54 (1.02–2.34)

p = 0.0416

 Frailty: frail vs. fit

1.47 (1.07–2.02)

p = 0.0182

 Male vs. female

1.12 (0.85–1.47)

p = 0.4202

 SOFA score (per one-point increase)

1.13 (1.1–1.17)

p < 0.0001

C. Results of the Cox analysis considering only acute patients admitted for other reason than sepsis (n = 3376)

 Age (per 5-year increase)

1.14 (1.06–1.23)

p = 0.0005

 Frailty: vulnerable vs. fit

1.11 (0.95–1.31)

p = 0.1939

 Frailty: frail vs. fit

1.48 (1.31–1.68)

p < 0.0001

 Male vs. female

1.16 (1.04–1.3)

p = 0.0064

 SOFA score (per one-point increase)

1.13 (1.12–1.14)

p < 0.0001