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Table 2 Characteristics of ICU lengh stay and therapeutic strategy

From: Mucormycosis in intensive care unit: surgery is a major prognostic factor in patients with hematological malignancy

 

Number of patients (%)

Survivors (n = 21)

Non-survivors (n = 53)

P-value

Type of ICU

0.11

 Medical, n (%)

53 (71.6)

13 (61.9)

40 (75.5)

 

 Surgical, n (%)

13 (17.6)

3 (14.3)

10 (18.9)

 

 Polyvalent, n (%)

8 (10.8)

5 (23.8)

3 (5.7)

 

Year of admission

0.70

Antifungal treatment

 Treatment including L-AmB

56 (75.7)

19 (90.5)

37 (69.8)

0.08

 L-AmB alone, n (%)

44 (59.5)

14 (66.7)

30 (56.6)

0.60

 Association of L-AmB + other drug, n (%)

12 (16.2)

5 (23.8)

7 (13.2)

0.30

 Triazole drug alone, n (%)

4 (5.4)

1 (4.8)

3 (5.7)

1

 Echinocandine alone, n (%)

1 (1.4)

0 (0)

1 (1.9)

1

 None, n (%)

13 (17.6)

1 (4.8)

12 (22.6)

0.09

 Delay of efficient antifungal treatment, mean (SD)a

9.5 (9.9)

8.2 (7.6)

10.1 (11.3)

0.45

Interventions

 Surgical intervention, n (%)

27 (36.5)

12 (57.1)

15 (28.3)

0.03

 Cutaneous resection

11 (14.9)

3 (14.3)

8 (15.1)

1

 Lung resection

7 (9.5)

6 (28.6)

1 (1.9)

0.002

 Amputation

2 (2.7)

2 (9.5)

0

0.08

 ENT resection

4 (5.4)

1 (4.8)

3 (5.7)

1

 Abdominal resection

3 (4.1)

0

3 (5.7)

0.55

 Vasopressors, n (%)

53 (71.6)

9 (42.9)

44 (83.0)

0.001

 Mechanical ventilation, n (%)

66 (89.2)

14 (66.7)

52 (98.1)

< 0.001

 Renal replacement therapy, n (%)

31 (41.9)

5 (23.8)

26 (49.1)

0.07

  1. Italic values indicate significance of P-value (P < 0.05)
  2. L-AmB liposomal amphotericin B
  3. aResults are expressed as mean (SD) and compared with Student’s t test