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Table 2 Association between sepsis markers and presence of proven bacterial infection at admission and day 2

From: Early sepsis markers in patients admitted to intensive care unit with moderate-to-severe diabetic ketoacidosis

Variables Admission Day 2
Episodes with PBI
(n = 20)
Episodes without PBI
(n = 82)
p-valuea Episodes with PBI
(n = 20)
Episodes without PBI
(n = 82)
p-valuea
Temperature, °C, median [IQR] 36.9 [36.2–38.0] 36.4 [35.7–36.8] 0.032 38.4 [37.1–39.0] 37.0 [36.8–37.3] <0.001
Feverb, n (%) 5 (25%) 3 (4%) 0.007 12 (60%) 7 (9%) <0.001
Hypothermiac, n (%) 4 (20%) 26 (32%) 0.410 0 (0%) 1 (1%) 1
WBC, G/L, median [IQR] 16.85 [14.25–22.15] 15.40 [12.30–22.50] 0.606 13.05 [8.68–18.23] 8.15 [6.68–10.20] <0.001
Leukocyte abnormalitiesd, n (%) 18 (90%) 62 (76%) 0.232 11 (55%) 14 (17%) 0.001
Neutrophils count, G/L, median [IQR] 13.30 [12.01–18.24] 13.71 [9.69–20.88] 0.673 10.79 [7.39–16.64] 5.38 [3.60–7.62] <0.001
NLCR; median [IQR] 14.04 [8.79–19.07] 11.40 [5.78–19.27] 0.359 11.54 [7.63–23.99] 2.84 [1.56–4.96] <0.001
Procalcitonin, ng/mL, median [IQR] 3.58 [1.87–11.24] 0.52 [0.19–1.38] <0.001 7.43 [2.63–22.70] 0.42 [0.14–1.42] <0.001
  1. PBI proven bacterial infection, IQR interquartile range 25–75%, WBC white blood cell count, NLCR neutrophils-to-lymphocytes count ratio
  2. aSignificant difference (p < 0.05) between episodes with and without proven bacterial infection are reported in the “p-value” column
  3. bFever: temperature > 38 °C
  4. cHypothermia: temperature < 36 °C
  5. dLeukocyte abnormalities: white blood cell count > 12,000/mm3 or < 4000/mm3