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Table 3 Organizational factors associated with the use of low tidal volume ventilation

From: Organizational factors associated with adherence to low tidal volume ventilation: a secondary analysis of the CHECKLIST-ICU database

 Absolute difference* (95% confidence interval)p value
Adjustment by severity of illness
 SAPS III− 2.64 (− 4.27 to − 1.00)0.001
 SOFA1.28 (− 0.40 to 2.92)0.131
Trial related
 Use of structured checklist5.10 (0.55 to 9.81)0.030
Hospital related
 Tertiary hospital0.10 (− 7.44 to 7.66)0.978
 Specialty hospital4.34 (− 3.76 to 12.49)0.306
 Number of hospital beds > 3247.43 (0.61 to 14.24)0.038
Organizational factors
 Board-certified consultant2.55 (− 3.33 to 8.44)0.406
 At least one nurse per 10 patients during all shifts17.24 (0.85 to 33.60)0.045
  1. SAPS Simplified Acute Physiology Score, SOFA Sequential Organ Failure Assessment
  2. Mixed-effect generalized linear model considering the phase of the study and the variables as fixed effect and the center as random effect. Continuous variables were standardized before inclusion in the model
  3. * Higher positive values indicate higher adherence to low tidal volume ventilation
  4. The effect of the phase of the study was not significant (2.34 [95% confidence interval − 0.96 to 5.87]; p = 0.161)
  5. The interaction between the phase of the study and the number of hospital beds was not significant (p = 0.254)
  6. The interaction between the phase of the study and the presence of one nurse for every 10 patients in all shifts was significant (p = 0.032)