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Table 1 Clinical, biological and hemodynamic characteristics

From: Acute myocarditis and multisystem inflammatory emerging disease following SARS-CoV-2 infection in critically ill children

 Value
Age, years median (range)10 (2.9–15)
Sex, no. (%)
 Male10 (50)
 Female10 (50)
 Admission delay from first symptoms, days, median (range)6 (1–10)
 PELOD-2 score at admission, median (range)10 (10–22)
Clinical description
 Fever, no. (%)20 (100)
 Abdominal pain, no. (%)20 (100)
 Skin rash, no. (%)10 (50)
 Conjunctivitis, no. (%)6 (30)
 Cheilitis, no. (%)5 (25)
 Adenitis (diameter > 1.5 cm), no. (%)2 (10)
 Glasgow Coma Scale, median (range)15 (4–15)
Hemodynamic features
 Tachycardia, no. (%)20 (100)
 Systemic arterial hypotension, no. (%)20 (100)
 Left ventricular ejection fraction, median (range), %35 (25–55)
Laboratory values, median (range)e
 Troponin, ng/mL269 (31–4607)
 Brain natriuretic peptide, pmol/La3405 (179–19013)
 Lactate, mmol/L3.6 (1–8,1)
 Creatinine clearance, mL/min/1,73 m297 (16–170)
 Albumin, g/L21 (17–26)
 Sodium, mmol/L131 (122–139)
 Alanine aminotransferase, IU/L27 (6–163)
 Platelets count, per mm3210, 000 (93,000–403,000)
 Neutrophil count, per mm310955 (1500–34200)
 Lymphocyte count, per mm31150 (380–7200)
 C-reactive protein, mg/L251 (94–458)
 Procalcitonin, ng/mLb46 (1,6–448)
 Fibrinogen, g/Lc7,2 (3,9–9)
 Inotropes and vasoactive drugs, no. (%)19 (95)
 Epinephrine, no. (%)12 (60)
 Median (range), µg/kg/min0.13 (0,1–0.5)
 Milrinone, no. (%)10 (50)
 Median (range), µg/kg/min0.45 (0.3–0.6)
 Dobutamine, no. (%)6 (30)
 Median (range), µg/kg/min7.5 (5–15)
 Norepinephrine, no. (%)4 (20)
 Median (range), µg/kg/min0.55 (0,2–1.2)
Mechanical ventilation
 Non-invasive ventilation, no. (%)11 (55)
 Invasive ventilation, no. (%)8 (40)
 High-flow nasal oxygen, no. (%)1 (5)
  1. aAvailable for 15 patients
  2. bAvailable for 16 patients
  3. cAvailable for 19 patients
  4. dHighest dosing during the PICU stay
  5. eWorst values within the first 24 h of PICU stay
  6. PELOD-2 Pediatric Logistic Organ Dysfunction 2 score
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