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Table 1 Characterization of proteoglycan core proteins in the glycocalyx.

From: Role of albumin in the preservation of endothelial glycocalyx integrity and the microcirculation: a review

Core proteinCore size (kDa)Number of subtypesStructural characteristicsLinked glycosaminoglycan (GAG)
Syndecan19–354Transmembrane proteinHeparan sulfate, chondroitin sulfate
Glypican57–696GPI-anchored proteinHeparan sulfate, chondroitin sulfate
Perlecan4001SecretedHeparan sulfate, chondroitin sulfate
Versican3701SecretedChondroitin sulfate, dermatan sulfate
Decorin401SecretedChondroitin sulfate, dermatan sulfate
Biglycan401SecretedChondroitin sulfate, dermatan sulfate
Minecan351SecretedKeratan sulfate
  1. GPI glycosylphosphatidylinositol