Table 1 Characterization of proteoglycan core proteins in the glycocalyx.
Core protein | Core size (kDa) | Number of subtypes | Structural characteristics | Linked glycosaminoglycan (GAG) |
|---|---|---|---|---|
Syndecan | 19–35 | 4 | Transmembrane protein | Heparan sulfate, chondroitin sulfate |
Glypican | 57–69 | 6 | GPI-anchored protein | Heparan sulfate, chondroitin sulfate |
Perlecan | 400 | 1 | Secreted | Heparan sulfate, chondroitin sulfate |
Versican | 370 | 1 | Secreted | Chondroitin sulfate, dermatan sulfate |
Decorin | 40 | 1 | Secreted | Chondroitin sulfate, dermatan sulfate |
Biglycan | 40 | 1 | Secreted | Chondroitin sulfate, dermatan sulfate |
Minecan | 35 | 1 | Secreted | Keratan sulfate |