Suspected IPN, n = 56 | Exposed, n = 33 | Unexposed, n = 23 | P value | |
---|---|---|---|---|
Age, y, median [IQR] | 58 [45.5;67.5] | 54.5 [45.5;64] | 63 [45;68.5] | 0.89 |
Males, n (%) | 47 [84] | 26 [78] | 21 [91] | 0.28 |
BMI, median [IQR] | 26.3 [23.6;29.5] | 25.7 [23, 29] | 26.9 [24.9;33] | 0.18 |
Origin of pancreatitis | ||||
Biliary | 16 (29) | 9 (27) | 7 (30.5) | 0.95 |
Alcohol abuse | 23 (51) | 14 (43) | 9 (39) | |
Otherb | 17 (30) | 10 (30) | 7 (30.5) | |
SAPS IIc, median [IQR] | 38 (28;52) | 37 [24;52] | 39 [31;52] | 0.73 |
CTSId, median [IQR] | 6 [4, 9] | 6 [4, 9] | 6 [4, 9] | 0.79 |
No organ failuree, n (%) | 1 (2) | 0 | 1 (5) | 0.76 |
1 or 2 organ failures, n (%) | 41 (73) | 24 (73) | 17 (74) | |
≥3 organ failures, n (%) | 14 (25) | 9 (27) | 5 (21) | |
Type of organ failure, n (%) | ||||
Respiratory failure | 52 (93) | 31 (94) | 21 (92) | 0.99 |
Mechanical ventilation | 43 (77) | 24 (73) | 19 (83) | 0.52 |
Circulatory failure | 34 (61) | 20 (61) | 14 (61) | 0.99 |
Renal failure | 33 (59) | 18 (55) | 15 (65) | 0.58 |
Time from ICU admission to first procedure for IPN, days, median [IQR] | 21 [12, 29] | 25 [15, 36] | 19 [10–25] | 0.61 |
IPN outcomes | ||||
Total number of procedures for IPN, median [IQR] | 2 [1–3] | 2 [1.5–3] | 2 [1–2.75] | 0.99 |
Confirmed IPN (positive sample culture), n (%) | 48 (85.7) | 30 (90) | 18 (78) | 0.25 |
Number of positive samples/total number of samples (%) | 106 (77) | 74/91 (81) | 32/46 (70) | 0.58 |
Patients developing a multidrug-resistant infectionf, n (%) | 15 (27) | 8 (24) | 6 (26) | 0.99 |
Patients developing an extensively drug resistant infectiong, n (%) | 10 (17.8) | 6 (18) | 4 (17) | 0.99 |
Patients with concomitant positive blood culture, n (%) | 18 (32) | 8 (24) | 10 (43) | 0.15 |
Other outcomes | ||||
Perforation of hollow organ, n (%) | 5 (9) | 4 (12) | 1 (4) | 0.63 |
Bowel ischemia, n (%) | 3 (5) | 2 (6) | 1 (4) | 0.99 |
Intestinal bleeding, n (%) | 11 (20) | 5 (15) | 6 (26) | 0.33 |
ICU stay, days, median [IQR] | 24.5 [7–47] | 23 [8–48] | 28 [6–44] | 0.54 |
Hospital stay, days, median [IQR] | 66.5 [42–96] | 68 [46.5–96] | 63 [42–101] | 0.68 |
ICU mortality, n (%) | 9 (16) | 5 (15) | 4 (17) | 0.99 |
Hospital mortality, n (%) | 9 (16) | 5 (15) | 4 (17) | 0.99 |