|
First line antimicrobial therapy, n (%)
|
|
Penicillin (amoxicillin and Peni M)
|
6 (11)
|
2 (6)
|
4 (17)
|
0.4
|
|
Amoxicillin–clavulanic acid
|
10 (18)
|
4 (12)
|
6 (26)
|
0.3
|
|
Piperacillin–tazobactam
|
16 (29)
|
9 (27)
|
7 (30)
|
1
|
|
Carbapenem
|
11 (19)
|
10 (30)
|
1 (4)
|
0.08
|
|
Cephalosporin
|
11 (19)
|
7 (21)
|
4 (17)
|
1
|
|
Fluoroquinolone
|
1 (2)
|
1 (3)
|
0
|
1
|
|
Cotrimoxazole
|
1 (2)
|
0
|
1 (4)
|
0.42
|
|
Metronidazole
|
33 (59)
|
17 (52)
|
16 (70)
|
0.51
|
|
Aminoglycoside
|
11 (19)
|
7 (21)
|
4 (17)
|
1
|
|
Anti-fungal
|
6 (11)
|
4 (12)
|
2 (9)
|
1
|
|
Time of overall antimicrobial therapy in ICU (median in days [IQR])
|
47 [28–77]
|
50 [28–88]
|
38.5 [26–61]
|
0.18
|
|
Number of overall different antimicrobial agents in ICU (median [IQR])
|
4 [2–6]
|
5 [4–8]
|
3 [2–5]
|
0.002
|
