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Table 1 Baseline characteristics

From: Multidisciplinary team approach in acute myocardial infarction patients undergoing veno-arterial extracorporeal membrane oxygenation

Variables

Total (n = 255)

Pre-ECMO team (n = 131)

Post-ECMO team (n = 124)

p value

Demographics

 Age, years

64.0 ± 11.8

63.4 ± 12.0

64.7 ± 11.5

0.384

 Male

200 (78.4)

105 (80.2)

95 (76.6)

0.593

 Body mass index, kg/m2

24.4 ± 3.5

23.8 ± 3.3

25.1 ± 3.7

0.004

Cardiovascular risk factors

 Hypertension

135 (52.9)

67 (51.1)

68 (54.8)

0.642

 Diabetes mellitus

128 (50.2)

67 (51.1)

61 (49.2)

0.852

 Dyslipidemia

37 (14.5)

20 (15.3)

17 (13.7)

0.861

 Chronic kidney disease

28 (11.0)

15 (11.5)

13 (10.5)

0.963

 History of myocardial infarction

61 (23.9)

17 (13.0)

44 (35.5)

< 0.001

 History of percutaneous coronary intervention

75 (29.4)

27 (20.6)

48 (38.7)

0.002

 History of cerebrovascular accident

27 (10.6)

18 (13.7)

9 (7.3)

0.139

Clinical presentation

 STEMI

164 (64.3)

89 (67.9)

75 (60.5)

0.266

 Systolic pressure, mmHga

73.0 (67.0–82.5)

74.0 (70.0–81.0)

71.0 (67.0–83.0)

0.698

 Out-of-hospital cardiac arrest

39 (15.3)

17 (13.0)

22 (17.7)

0.377

 In-hospital cardiac arrest

163 (63.9)

82 (62.6)

81 (65.3)

0.747

 Left ventricular ejection fraction, %

32.0 (25.0–41.0)

32.0 (25.0–45.0)

30.0 (24.5–40.0)

0.542

Laboratory findings

 Hemoglobin, g/dL

12.5 (10.4–14.7)

12.5 (10.5–14.8)

12.5 (10.2–14.6)

0.565

 Prothrombin time, %

81.0 (63.0–92.0)

81.0 (63.0–91.0)

83.5 (62.0–95.5)

0.318

 Total bilirubin, mg/dL

0.8 (0.5–1.1)

0.9 (0.6–1.1)

0.7 (0.4–1.0)

0.014

 Creatinine, mg/dL

1.3 (1.0–1.8)

1.2 (1.0–1.8)

1.3 (1.0–1.7)

0.644

 Lactic acid, mmol/L

5.5 (2.7–9.5)

6.1 (2.9–10.5)

4.7 (2.5–7.9)

0.060

 Peak troponin I, ng/mL

156.5 (39.3–486.5)

153.5 (44.8–489.4)

159.6 (31.1–481.4)

0.591

 Peak CK-MB, ng, mL

233.6 (60.3–423.3)

254.2 (51.5–484.2)

202.1 (62.3–383.2)

0.413

Severity score

 ENCOURAGE score

20.0 (14.0–24.5)

19.0 (14.0–24.0)

20.5 (16.0–25.0)

0.304

 AMI-ECMO score

20.0 (16.0–27.0)

21.0 (16.0–27.0)

19.0 (16.0–27.0)

0.749

 SOFA score

11.0 (9.0–13.0)

11.0 (9.0–13.0)

11.0 (9.0–12.0)

0.257

Angiographic findings

 Infarct-related artery

0.173

  Left anterior descending artery

114 (44.7)

62 (47.3)

52 (41.9)

 

  Left circumflex artery

30 (11.8)

15 (11.5)

15 (12.1)

 

  Right coronary artery

47 (18.4)

21 (16.0)

26 (21.0)

 

  Left main coronary artery

59 (23.1)

28 (21.4)

31 (25.0)

 

  Unknown

5 (2.0)

5 (3.8)

0 (0)

 

 Multivessel disease

201 (78.8)

98 (74.8)

103 (83.1)

0.144

  1. Data are presented as n (%), means ± standard deviations, or medians (interquartile ranges)
  2. AMI acute myocardial infarction, CK-MB creatine kinase-myocardial band, ECMO extracorporeal membrane oxygenation, STEMI ST-segment elevation myocardial infarction
  3. aValue measured just before ECMO insertion procedure in patients with refractory cardiogenic shock without cardiac arrest at the time of ECMO insertion