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Table 3 Summary of pharmacokinetic and pharmacodynamic parameters of TGC

From: Pharmacokinetics of tigecycline in critically ill patients with liver failure defined by maximal liver function capacity test (LiMAx)

Measure Cmax (mg/L) AUC (mg h/L)   MIC (mg/L) AUC/MIC
  0.805 5596 Gram positive without MRSA 0.12 46.63
Gram negative 0.5 11.192
  1. AUC: area under the concentration–time curve over 12 h; MIC: minimum inhibitory concentration