Pharmacokinetics of tigecycline in critically ill patients with liver failure defined by maximal liver function capacity test (LiMAx)

Annals of Intensive Care

Table 3 Summary of pharmacokinetic and pharmacodynamic parameters of TGC

Measure	C_max (mg/L)	AUC (mg h/L)		MIC (mg/L)	AUC/MIC
	0.805	5596	Gram positive without MRSA	0.12	46.63
	0.805	5596	Gram negative	0.5	11.192

AUC: area under the concentration–time curve over 12 h; MIC: minimum inhibitory concentration