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Annals of Intensive Care

Table 5 Multiple linear regression model: co-factors predicting TGC Cmax

From: Pharmacokinetics of tigecycline in critically ill patients with liver failure defined by maximal liver function capacity test (LiMAx)

 

Beta

p-value

Constant

 

< 0.001

Total bilirubin (mg/dL)

0.495

0.001

LiMAx value (µk/kg/h)

− 0.293

0.044

Lactate

–

0.336

MELD score

–

0.211

INR

–

0.558

  1. LiMAx value (maximum liver function capacity), total bilirubin, Lactate, MELD score (model for end-stage liver disease) and INR (international normalized ratio)
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