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Table 4 Performances of CPIS for the diagnosis of VAP in patients with VA-LRTI

From: Accuracy of the clinical pulmonary infection score to differentiate ventilator-associated tracheobronchitis from ventilator-associated pneumonia

  CPIS value Se Sp PPV NPV LR+ LR- Youden index
Derivation cohort ≥ 5 0.83 0.51 0.66 0.72 1.68 0.34 0.34
≥ 6 0.68 0.69 0.71 0.65 2.17 0.46 0.37
≥ 7 0.51 0.88 0.83 0.61 4.13 0.56 0.39
Validation cohort ≥ 5 0.78 0.34 0.70 0.44 1.19 0.64 0.12
≥ 6 0.60 0.70 0.80 0.48 2 0.57 0.3
≥ 7 0.45 0.89 0.88 0.45 3.92 0.62 0.34
  1. CPIS Clinical pulmonary infection score, Se Sensitivity, Sp Specificity, PPV Positive predictive value, NPV Negative predictive value, LR + Positive likelihood ratio, LR- Negative likelihood ratio