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Table 1 Demographic characteristics, respiratory mechanics, and hemodynamic parameters, according to respiratory system elastance

From: Is hypoxemia explained by intracardiac or intrapulmonary shunt in COVID-19-related acute respiratory distress syndrome?

Characteristic All patients
n = 60
Lower Ers
n = 30
Higher Ers
n = 30
P value
Age (y) 62 [51–72] 64 [50–73] 58 [53–69] 0.36
Male gender (%) 50 (83) 27 (90) 23 (77) 0.17
Body mass index (kg/m2) 27 [24–32] 28 [24–32] 27 [25–31] 0.76
PEEP (cmH20) 11 [9–12] 12 [9–12] 10 [8–12] 0.13
Driving pressure (cmH2O) 12 [11–15] 11 [9–12] 14 [13–16] < 0.001
Crs (mL/cmH2O) 32 [27–40] 40 [36–45] 27 [21–30] < 0.001
Ers (cmH2O/L) 32 [24–34] 25 [22–28] 38 [33–48] < 0.001
PaO2/FiO2 (mmHg) 142 [107–194] 170 [131–224] 119 [72–177] < 0.01
PaCO2 (mmHg) 42 [38–47] 42 [36–46] 44 [40–51] 0.07
LVEF (%) 60 [49–6] 60 [49–68] 60 [48–70] 0.88
Cardiac index (L/min/m2) 2.78 [2.42–3.40] 2.69 [2.39–3.23] 2.95 [2.44–3.71] 0.24
RV/LV area ratio 0.6 [0.50–0.70] 0.6 [0.50–0.73] 0.58 [0.49–0.70] 0.96
Acute cor pulmonale (%) 26 (43) 13 (43) 13 (43) > 0.99
PFO shunt (%) 6 (10) 2 (7) 4 (13) 0.67
TPBT (%) 12 (20) 8 (27) 4 (13) 0.20
  1. Ers: respiratory system elastance; PEEP: positive end-expiratory pressure; Crs: respiratory system compliance; PaO2/FiO2: ratio of partial pressure of oxygen in arterial blood and fraction of inspired oxygen; PaCO2: partial pressure of carbon dioxide in arterial blood; LVEF: left ventricle ejection fraction; RV: right ventricle; LV: left ventricle; PFO: patent foramen ovale; TPBT: transpulmonary bubble transit
  2. Mann–Whitney test for continuous variables and Chi-square test or Fisher exact test for categorical variables