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Table 1 Patient demographics before and after propensity matching

From: Mortality and morbidity of low-grade red blood cell transfusions in septic patients: a propensity score-matched observational study of a liberal transfusion strategy

  Unmatched groups Standardized difference P value Propensity-matched groups Standardized difference P value
Control N = 405 RBCaN = 459 Control N = 237 RBC N = 237
Pre-existing conditions
 Age, mean (SDb) 64 (16) 65 (15) 0.047 0.490 65 (15) 65 (15) 0.010 0.914
 Male gender, no (%) 233 (57) 234 (51) 0.131 0.054 130 (55) 138 (58) 0.068 0.460
 Blood malignancyc, no (%) 16 (4.4) 42 (9.2) 0.187 0.007 12 (5.1) 14 (5.9) 0.037 0.687
 COPDd, no (%) 42 (10) (0.305) 52 (11) 0.030 0.652 29 (12) 28 (12) 0.013 0.888
 Cirrhosis, no (%) 17 (4.2) 12 (2.6) 0.087 0.198 11 (4.6) 8 (3.4) 0.065 0.483
 Immunosuppressione, no (%) 30 (7.4) 54 (12) 0.148 0.031 18 (7.6) 19 (8.0) 0.016 0.864
 Malignancyf, no (%) 43 (11) 73 (16) 0.156 0.023 31 (13) 33 (14) 0.025 0.789
 Nosocomial infectiong, no (%) 33 (8.1) 44 (9.6) 0.051 0.460 21 (8.9) 24 (10) 0.043 0.639
 Airway infection, no (%) 112 (28) 116 (25) 0.054 0.428 63 (27) 63 (27 0 1.000
 Surgeryh, no (%) 64 (16) 99 (22) 0.148 0.031 40 (17) 48 (20) 0.087 0.346
 GIi-bleeding, no (%) 0 (0) 6 (1.3) 0.163 0.021 0 (0) 0 (0) 0.000 1.000
 DICj, no (%) 25 (6.2) 33 (7.2) 0.041 0.552 19 (8.0) 14 (5.9) 0.083 0.368
 I.C.k volume effect, no (%) 2 (0.5) 4 (0.9) 0.046 0.505 2 (0.8) 2 (0.8) 0 1.000
Physiological and laboratory variables at admissionl, mean (SD)
 Heart rate, mean (SD) 107 (23) 109 (24) 0.085 0.216 106 (23) 106 (25) 0.013 0.889
 SBPm, (mmHg) 108 (30) 107 (29) 0.052 0.450 107 (30) 108 (31) 0.044 0.634
 Lactate (mmol/L) 3.4 (3.2) 3.5 (2.7) 0.027 0.691 3.4 (3.2) 3.4 (2.7) 0 0.996
 Norepinephrine (µg/min) 7.0 (12) 11.6 (20) 0.285 < 0.001 9.0 (13) 7.7 (11) 0.108 0.241
 Temperature (°Celcius) 37.4 (1.5) 37.4 (1.4) 0.035 0.617 37.3 (1.5) 37.3 (1.4) 0.007 0.940
 PaO2/FiO2 (kPa) 23 (15) 22 (16) 0.040 0.588 23 (15) 22 (15) 0.040 0.665
 Leucocytes (× 109/L) 16 (18) 14 (19) 0.093 0.197 16 (20) 15 (20) 0.038 0.683
 Platelets (× 109/L) 188 (130) 182 (135) 0.044 0.517 187 (129) 185 (120) 0.018 0.845
 pH 7.13 (1.5) 7.31 (0.50) 0.261 <0.001 7.34 (0.12) 7.34 (0.11) 0.042 0.647
 Bilirubin (µmol/L) 24 (35) 25 (46) 0.010 0.891 24 (33) 26 (50) 0.053 0.561
 Creatinine (µmol/L) 172 (126) 180 (141) 0.063 0.360 181(130) 175 (133) 0.042 0.645
 PT/INRn 1.58 (0.85) 1.62 (0.82) 0.040 0.550 1.58 (0.70) 1.59 (0.78) 0.005 0.956
 APTTo (sec) 42 (19) 45 (17) 0.178 0.009 43 (18) 42 (14) 0.050 0.586
  1. aLow-grade red blood cell transfusion defined as < 670 ml any of the first 5 days
  2. bStandard deviation
  3. cLymphoma, acute leukaemia or myeloma
  4. dChronic obstructive pulmonary disease
  5. eChronic steroid treatment correlative to ≥ 0.3 mg/kg prednisolone/day, radiation, or chemo therapy
  6. fCancer spread beyond the regional lymph nodes
  7. gInfection that developed after ≥ 48 h in hospital or secondary to surgical or medical procedure
  8. hBefore admission to intensive care
  9. iGastro-intestinal
  10. jDisseminated intravascular coagulopathy
  11. kIntra-cranial
  12. lFirst value within 90 min after admission except for “Norepinephrine” which is the mean dose the first 12 h
  13. mSystolic blood pressure
  14. nProthrombin time
  15. oActivated partial thromboplastin time