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Table 3 Clinical and demographic characteristics of infected non-septic patients according to clinical course during the 72 h after admission to the emergency department

From: Prognostic performance of endothelial biomarkers to early predict clinical deterioration of patients with suspected bacterial infection and sepsis admitted to the emergency department

Variable Deterioration (n = 48) No deterioration (n = 185) Total (n = 233) p value
Male 24 (50.00) 87 (47.03) 111 (47.64) 0.837a
Age (years) 66 [42–73] 52 [35–67] 55 [36–69] 0.004b
Number of comorbidities     0.132a
 0 26 (54.17) 128 (69.19) 154 (66.09)  
 1 15 (31.25) 36 (19.46) 51 (21.89)  
 > 1 7 (14.58) 21 (11.35) 28 (12.02)  
Charlson score 3 [0.75–5] 1 [0–3] 1 [0–3] 0.001b
qSOFA     0.357a
 0 22 (45.83) 101 (54.59) 123 (52.79)  
 1 26 (54.17) 84 (45.41) 110 (47.21)  
Site of infection     0.132a
 Pulmonary 14 (29.17) 27 (14.59) 41 (17.60)  
 Urinary 13 (27.08) 62 (33.52) 75 (32.19)  
 Abdominopelvic 13 (27.08) 58 (31.35) 71 (30.47)  
 Others 8 (16.67) 38 (20.54) 46 (19.74)  
Hospitalization after ED discharge     0.758c
 Ward 29 (61.69) 100 (56.82) 129 (57.84)  
 Surgery 14 (29.79) 64 (36.36) 78 (34.98)  
 Stepdown unit 2 (4.26) 7 ( 3.98) 9 (4.04)  
 ICU 2 (4.26) 5 ( 2.84) 7 (3.14)  
ATB delay (hours) 5.08 [3.4–8.0] 4.34 [2.6–7.0] 4.60 [2.7–7.6] 0.109b
LOS (days) 6.5 [3.8–10] 4 [3–6] 4 [3–7] < .001b
D-28 mortality 1 (2.08) 2 (1.08) 3 (1.29) 0.501c
  1. Data are expressed either as n (%) or as median [Q1, Q3]
  2. ATB antibiotherapy, ICU intensive care unit, LOS length of stay
  3. a Pearson χ2 test
  4. b Wilcoxon–Mann–Whitney
  5. c Fisher