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Table 4 Factors predictive of early deterioration using univariate and multivariate analyses in non-septic infected patients (SOFA score < 2) at inclusion (T0) (n = 223)

From: Prognostic performance of endothelial biomarkers to early predict clinical deterioration of patients with suspected bacterial infection and sepsis admitted to the emergency department

Variable Univariate analysis Multivariate analysis
p value IQR OR [95% CI] p value IQR OR [95% CI]
Lactates ns ns
CRP ns ns
qSOFA score ns ns
Age 0.0042 1.27 [1.08–1.51] ns
Charlson score 0.0029 1.25 [1.08–1.44] ns
PCT ns ns
sUPAR 0.022 1.49 [1.06–2.10] ns
sVEGFR2 0.0002 2.76 [1.68–4.75] 0.0017 2.35 [1.41–4.12]
sUPAR -sVEGFR2 combination 0.0005 1.74 [1.28–2.41] 0.019 1.52 [1.07–2.19]
  1. CRP C-reactive protein, qSOFA quick Sequential Organ Failure Assessment, PCT procalcitonin, IQR interquartile, OR odds ratio, CI confidence interval