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Annals of Intensive Care

Table 2 Diaphragm thickness and thickening fraction based on changes in thickness in first 4 days of mechanical ventilation

From: The impact of critical illness on the expiratory muscles and the diaphragm assessed by ultrasound in mechanical ventilated children

 

Overall study population (n = 34)

> 10% decrease (n = 15)

Within 10% of baseline (n = 10)

>10% increase (n = 9)

P value

Baseline measurements

 Thickness at end-expiration (mm)

1.5 (1–1.6)

1.6 (1.1–1.6)

1.4 (0.8–1.6)

1.1 (1.0–1.5)

0.253

 Thickening fraction (%)

10.7 (7.5–16.2)

9.1 (4.9–13.0)

16.3 (11.9–23.6)

10.7 (7.3–13.2)

0.029a

Last measurements (day ≤ 4)

 Thickness at end-expiration (mm)

1.3 (0.9–1.6)

1.2 (0.8–1.4)

1.3 (0.9–1.7)

1.6 (1.3–1.7)

0.017b

 Thickening fraction (%)

12.4 (5.7–16.6)

7.1 (0.9–15.6)

12.6 (9.7–15.3)

16 (11.0–21.7)

0.147

Average over first 4 days

 Thickening fraction (%)

11.4 (9.7–14.5)

9.9 (8.6–12.2)

12.8 (10.5–18.1)

12.5 (10.6–16.4)

0.051c

  1. Data are presented as median (IQR)
  2. Patients are divided into 3 subgroups according to the change in diaphragm thickness during ≤ 4 days of MV
  3. IQR, interquartile range, MV, mechanical ventilation
  4. aBetween patients with > 10% decrease and ≤ 10% change in diaphragm muscle thickness, and between patients with > 10% increase and ≤ 10% change in diaphragm muscle thickness
  5. bBetween patients with > 10% increase and patients ≤ 10% change in diaphragm thickness
  6. cBetween patients with > 10% decrease and ≤ 10% change in diaphragm thickness
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