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Table 4 Characteristics and measurements of diaphragm and expiratory muscles for patients with successful and failed extubation

From: The impact of critical illness on the expiratory muscles and the diaphragm assessed by ultrasound in mechanical ventilated children

 

Successful extubation (n = 31)

Failed extubation (n = 3)

P value

Clinical characteristics

 Age, months

4.0 (1–25)

15 (13–15)

0.142

 Body weight, kg

6.0 (4.3–13.5)

8.9 (8.0–8.9)

0.261

 Duration of MV, h

103 (67–154)

268 (120–268)

0.073

 Ventilator settingsa

  Peak-PEEP, cmH2O

15 (12–20)

15 (12.7–15)

0.855

  Tidal volume, ml/kg

6.6 (6.0–7.3)

6.4 (5.8–6.4)

0.524

Diaphragm

 Baseline thickness

1.4 (1.0–1.6)

1.6 (1.0–1.6)

0.693

 Change in thickness (% of baseline)

10.7 (9.5–14.4)

12.5 (12.1–12.5)

0.785

 Average TFdi (first 4 days)

− 5.96 (− 20.4–10.6)

− 12.4 (− 21.9–− 12.4)

0.237

 TFdi before extubation

15.2 (9.6–19.1)

4.0 (0–4.0)

0.108

Expiratory muscles (OE, OI, TA)

 Baseline thickness

4.2 (3.6–5.3)

4.2 (3.5–4.2)

0.649

 Change in thickness (% of baseline)

− 3.89 (− 16.6–9.5)

− 33.8 (− 43–− 33.8)

0.014

 Average TF (first 4 days)

5.38 (2.8–6.8)

3.46 (2.0–3.46)

0.236

 TF before extubation

6.5 (1.9–10.6)

3.5 (0–3.5)

0.395

Rectus abdominis (RA)

 Baseline thickness

1.9 (1.6–2.3)

1.6 (1.2–1.6)

0.485

 Change in thickness (% of baseline)

8.12 (–0.9–22.6)

0.54 (–16.8–0.54)

0.564

 Average TF (first 4 days)

2.33 (1.7–4.1)

2.5 (0.6–2.50)

0.785

 TF before extubation

1.3 (0–4.2)

1.4 (0–1.4)

0.975

  1. Results are presented as median [IQR]; successful extubation group (Q1–Q3) and failed extubation group (Q1–Q2)
  2. IQR, interquartile range, TF, thickening fraction; TFdi, thickening fraction diaphragm at end-inspiration
  3. OE, m. obliquus externa; OI, m. obliquus interna; TA, m. transversus abdominis; RA, m. rectus abdominis
  4. aThe ventilation settings are shown as an average over the first 4 days of mechanical ventilation