Respiratory virus-associated infections in HIV-infected adults admitted to the intensive care unit for acute respiratory failure: a 6-year bicenter retrospective study (HIV-VIR study)

Annals of Intensive Care

Table 5 Multivariate analysis of the risk factors for complicated course in 123 HIV-infected patients admitted to the ICU for acute respiratory failure

	Univariate analysis			Multivariate analysis
Variables	Odds ratio	95% confidence interval	p value	Odds ratio	95% confidence interval	p value
Chronic dialysis	3.1	[0.73–13.15]	0.12
Cirrhosis (Child B–C)	2.76	[0.49–15.65]	0.25
Cancer or hematologic malignancy	2.76	[0.49–15.65]	0.25
Use of vasopressor^a	7.76	[1.71–35.29]	< 0.01	7.2	[1.5–35.4]	0.01
Pleural effusion	2.34	[0.68–8.1]	0.18	3.6	[1.06–12.2]	0.04
HIV viral load^b	1.14	[0.89–1.45]	0.31
PaO2/FIO2 ratio^b	0.995	[0.99–1]	0.05
Urea^b	1.035	[1–1.07]	0.06
Alkaline phosphatase^b	1.008	[1–1.01]	< 0.01	1.008	[1.002–1.01]	0.006
Minimal platelet count^b	0.996	[0.99–1]	0.05
Fibrinogen^b	0.79	[0.59–1.06]	0.12
Minimal prothrombin time^b	0.979	[0.95–1.01]	0.12

Complicated course was defined as death from any cause within 28 days following the ICU admission and/or mechanical ventilation > 7 days
^aDuring the first hour of the ICU stay
^bRefers to values at ICU admission