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Table 5 Multivariate analysis of the risk factors for complicated course in 123 HIV-infected patients admitted to the ICU for acute respiratory failure

From: Respiratory virus-associated infections in HIV-infected adults admitted to the intensive care unit for acute respiratory failure: a 6-year bicenter retrospective study (HIV-VIR study)

  Univariate analysis Multivariate analysis
Variables Odds ratio 95% confidence interval p value Odds ratio 95% confidence interval p value
Chronic dialysis 3.1 [0.73–13.15] 0.12    
Cirrhosis (Child B–C) 2.76 [0.49–15.65] 0.25    
Cancer or hematologic malignancy 2.76 [0.49–15.65] 0.25    
Use of vasopressora 7.76 [1.71–35.29] < 0.01 7.2 [1.5–35.4] 0.01
Pleural effusion 2.34 [0.68–8.1] 0.18 3.6 [1.06–12.2] 0.04
HIV viral loadb 1.14 [0.89–1.45] 0.31    
PaO2/FIO2 ratiob 0.995 [0.99–1] 0.05    
Ureab 1.035 [1–1.07] 0.06    
Alkaline phosphataseb 1.008 [1–1.01] < 0.01 1.008 [1.002–1.01] 0.006
Minimal platelet countb 0.996 [0.99–1] 0.05    
Fibrinogenb 0.79 [0.59–1.06] 0.12    
Minimal prothrombin timeb 0.979 [0.95–1.01] 0.12    
  1. Complicated course was defined as death from any cause within 28 days following the ICU admission and/or mechanical ventilation > 7 days
  2. aDuring the first hour of the ICU stay
  3. bRefers to values at ICU admission