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Table 2 Respiratory parameters before ECCO2R and after ECCO2R initiation combined with RR adjustment

From: Physiological effects of adding ECCO2R to invasive mechanical ventilation for COPD exacerbations

 

Without ECCO2R

ECCO2R with RR adjustment

p

RR (/min.)

12 (12; 12)

12 (11; 14)

0.4236

VT (mL/Kg PBW)

8.0 (8.0; 8.0)

8.0 (8.0; 8.0)

1

FiO2

32.5 (30; 40)

35 (30; 40)

0.75

PEEPi (cmH20)

8.5 (7.0; 10.0)

8.0 (5.5; 9.5)

0.1191

Pplateau (cmH20)

15.5 (14.0; 17.5)

16.0 (14.0; 17.5)

0.6323

Ppeak (cmH2O)

42.0 (37.5; 49.5)

41.5 (37.5; 51.5)

0.6323

FRC (mL)

3544 (1908; 4849)

2830 (2066; 3818)

0.3013

VT/TE (mL/sec.)

140 (114; 153)

140 (107; 149)

0.8457

PaCO2 (mmHg)

68 (63; 76)

49 (46; 55)

0.0005

PaO2 (mmHg)

73 (60; 85)

78 (69; 94)

0.1831

pH

7.25 (7.23; 7.29)

7.35 (7.32; 7.40)

0.0005

SatHbO2 (%)

93 (88; 95)

96 (95; 97)

0.0337

VCO2resp (mL/min.)

203 (150; 243)

121 (101; 155)

0.0015

  1. RR respiratory rate, VT tidal volume, PBW predicted body weight, PEEPi intrinsic Positive End Expiratory Pressure, Pplateau plateau pressure, Ppeak peak pressure, FRC functional residual capacity, VT/TE ratio of tidal volume by expiratory time; PaCO2 arterial partial pressure in carbon dioxide, PaO2 arterial partial pressure in oxygen, SatHbO2 Oxygen hemoglobin saturation, VCO2resp native lungs' CO2 elimination
  2. Results are expressed as median (IQR)