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Table 2 Respiratory parameters before ECCO2R and after ECCO2R initiation combined with RR adjustment

From: Physiological effects of adding ECCO2R to invasive mechanical ventilation for COPD exacerbations

  Without ECCO2R ECCO2R with RR adjustment p
RR (/min.) 12 (12; 12) 12 (11; 14) 0.4236
VT (mL/Kg PBW) 8.0 (8.0; 8.0) 8.0 (8.0; 8.0) 1
FiO2 32.5 (30; 40) 35 (30; 40) 0.75
PEEPi (cmH20) 8.5 (7.0; 10.0) 8.0 (5.5; 9.5) 0.1191
Pplateau (cmH20) 15.5 (14.0; 17.5) 16.0 (14.0; 17.5) 0.6323
Ppeak (cmH2O) 42.0 (37.5; 49.5) 41.5 (37.5; 51.5) 0.6323
FRC (mL) 3544 (1908; 4849) 2830 (2066; 3818) 0.3013
VT/TE (mL/sec.) 140 (114; 153) 140 (107; 149) 0.8457
PaCO2 (mmHg) 68 (63; 76) 49 (46; 55) 0.0005
PaO2 (mmHg) 73 (60; 85) 78 (69; 94) 0.1831
pH 7.25 (7.23; 7.29) 7.35 (7.32; 7.40) 0.0005
SatHbO2 (%) 93 (88; 95) 96 (95; 97) 0.0337
VCO2resp (mL/min.) 203 (150; 243) 121 (101; 155) 0.0015
  1. RR respiratory rate, VT tidal volume, PBW predicted body weight, PEEPi intrinsic Positive End Expiratory Pressure, Pplateau plateau pressure, Ppeak peak pressure, FRC functional residual capacity, VT/TE ratio of tidal volume by expiratory time; PaCO2 arterial partial pressure in carbon dioxide, PaO2 arterial partial pressure in oxygen, SatHbO2 Oxygen hemoglobin saturation, VCO2resp native lungs' CO2 elimination
  2. Results are expressed as median (IQR)