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Table 3 Work of breathing (WOB) measurements in 5 patients with and without ECCO2R

From: Physiological effects of adding ECCO2R to invasive mechanical ventilation for COPD exacerbations

 

ECCO2R+

ECCO2R−

p

WOB (J/L)

1.10 (0.8; 1.40)

1.50 (0.9; 2.80)

0.0625

WOB (J/min.)

11.70 (7.50; 15.00)

22.60 (13.90; 34.70)

0.0625

WOB (J/breath)

0.59 (0.39; 0.79)

0.94 (0.56; 1.29)

0.0625

RR (/min.)

19 (19; 20)

24 (24; 25)

0.1250

VCO2tot (mL/min.)

308 (307; 347)

321 (312; 417)

0.3125

VCO2resp (mL/min.)

242 (240; 280)

321 (312; 417)

0.0625

  1. ECCO2R+ treatment with ECCO2R while breathing at a low pressure support level, ECCO2R− after switching the sweep gas flow to 0 L/min. for 1 h, WOB: work of breathing expressed as Joules per liter of minute ventilation (J/L) or as Joules per breath (J/breath), VCO2tot whole body CO2 elimination, VCO2resp native lungs CO2 elimination
  2. Results are expressed as median (IQR)