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Table 3 Work of breathing (WOB) measurements in 5 patients with and without ECCO2R

From: Physiological effects of adding ECCO2R to invasive mechanical ventilation for COPD exacerbations

  ECCO2R+ ECCO2R− p
WOB (J/L) 1.10 (0.8; 1.40) 1.50 (0.9; 2.80) 0.0625
WOB (J/min.) 11.70 (7.50; 15.00) 22.60 (13.90; 34.70) 0.0625
WOB (J/breath) 0.59 (0.39; 0.79) 0.94 (0.56; 1.29) 0.0625
RR (/min.) 19 (19; 20) 24 (24; 25) 0.1250
VCO2tot (mL/min.) 308 (307; 347) 321 (312; 417) 0.3125
VCO2resp (mL/min.) 242 (240; 280) 321 (312; 417) 0.0625
  1. ECCO2R+ treatment with ECCO2R while breathing at a low pressure support level, ECCO2R− after switching the sweep gas flow to 0 L/min. for 1 h, WOB: work of breathing expressed as Joules per liter of minute ventilation (J/L) or as Joules per breath (J/breath), VCO2tot whole body CO2 elimination, VCO2resp native lungs CO2 elimination
  2. Results are expressed as median (IQR)