Table 3 Clinical and physiological variables of patients receiving respiratory support outside the ICU
Conventional oxygen therapy (N = 114) | Non-invasive respiratory supporta (N = 127) | p-value | |
|---|---|---|---|
Age | 80 (65–83) | 75 (67–82) | NS |
Male, n (%) | 72 (63.2) | 101 (79.5) | 0.0048 |
Comorbidities (n, %) | |||
None | 0 (0.0) | 0 (0.0) | |
COPD | 18 (15.8) | 21 (16.5) | NS |
Diabetes | 19 (16.7) | 29 (22.8) | NS |
Obesity | 23 (20.9) | 15 (11.8) | 0.0570 |
HIV infection | 0 (0.0) | 0 (0.0) | |
Immunocompromised state | 4 (3.5) | 2 (1.6) | NS |
Cardiovascular disease | 73 (64.0) | 77 (60.6) | NS |
Cerebrovascular disease | 20 (17.5) | 9 (7.1) | 0.0127 |
Chronic kidney disease | 13 (11.4) | 11 (8.7) | NS |
Chronic liver failure | 2 (1.8) | 1 (0.8) | NS |
Active neoplasm | 6 (5.3) | 2 (1.6) | NS |
Other | 23 (20.2) | 17 (13.4) | NS |
Physiological variablesb | |||
PaO2 pressure (mmHg) | 65 (54–77) | 59 (54–70) | 0.0079 |
PaO2/FiO2 ratio | 269 (198–323) | 183 (102–265) | < 0.0001 |
PaCO2 (mmHg) | 35 (31–38) | 33 (30–38) | NS |
pH | 7.45 (7.41–7.48) | 7.46 (7.44–7.50) | 0.0234 |
Respiratory rate (breath/min) | 24 (18–26) | 24 (20–29) | NS |
Base excess (mEq/L) | 0.50 (− 2.53; 2.15) | 0.85 (–0.85; 2.00) | NS |
28-day mortality (n; %) | 67 (58.8) | 66 (52.0) | NS |