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Annals of Intensive Care

Table 2 Risk factors for liver transplantation (n = 22) versus survival without (n = 75) on day-28

From: pCLIF-SOFA is a reliable outcome prognostication score of critically ill children with cirrhosis: an ESPNIC multicentre study

Characteristics

Univariate analysis

Multivariable analysis

Odds ratio

p value

Odds ratio

p value

Comorbidity

0.18 (0.06–0.56)

0.003

0.03 (0.00–0.53)

0.017

Growth failure

0.80 (0.26–2.48)

0.711

  

ACLF

17.75 (4.79–65.7)

0.000

6.12 (1.06–35.03)

0.042

Sepsis

1.58 (0.60–4.12)

0.344

  

Biliary atresia

1.79 (0.67–4.12)

0.241

  

INR ≥ 2.5

5.22 (1.88–14.5)

0.001

  

Bilirubin ≥ 300 μmol/L

2.88 (1.00–8.30)

0.050

  

pCLIF-SOFA

1.21 (1.04–1.40)

0.011

1.3 (1.04–1.67)

0.019

PELD

1.06 (1.01–1.11)

0.009

  
  1. Odds ratio are expressed as 95% (confidence interval). On multivariable analysis, centre effect was not significant (p = 0.20)
  2. ACLF acute-on-chronic liver failure, BA biliary atresia, INR International Normalized Ratio, pCLIF-SOFA Paediatric Chronic Liver Failure-Sequential Organ Failure Assessment score, PELD paediatric end-stage liver disease
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