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Table 3 Risk factors for liver transplantation (n = 29) versus survival without (n = 63) on day-60

From: pCLIF-SOFA is a reliable outcome prognostication score of critically ill children with cirrhosis: an ESPNIC multicentre study

Characteristics

Univariate analysis

Multivariable analysis

Odds ratio

p value

Odds ratio

p value

Comorbidity

0.12 (0.04–0.35)

0.001

0.10 (0.03–0.33)

0.001

Growth failure

2.02 (0.76–5.39)

0.158

  

ACLF

9.01 (2.55–31.78)

0.001

5.02 (1.24–20.23)

0.023

Sepsis

1.74(0.71–4.25)

0.225

  

Biliary atresia

1.37 (0.56–3.34)

0.485

  

INR ≥ 2.5

2.71 (1.04–7.08)

0.041

  

Bilirubin ≥ 300 μmol/L

2.02 (0.72–5.61)

0.177

  

pCLIF-SOFA

1.19 (1.03–1.38)

0.016

  

pCLIF-SOFA ≥ 7

2.85 (1.06–7.64)

0.036

5.07 (1.47–17.47)

0.010

PELD

1.05 (1.00–1.13)

0.021

  
  1. Odds ratio are expressed as 95% (confidence interval). On multivariable analysis, centre effect was not significant (p = 0.13)
  2. ACLF acute-on-chronic liver failure, INR International Normalized Ratio, pCLIF-SOFA Paediatric Chronic Liver Failure-Sequential Organ Failure Assessment score, PELD paediatric end-stage liver disease