From: Management of pharmaceutical and recreational drug poisoning
Dosing methods | Interest/limits | ||
---|---|---|---|
Immunological | Plasma or serum | Acetaminophen, salicylic acid (active metabolite of acetylsalicylic acid), digoxin, valproic acid | Automated assays (available in less than 120Â min) Few potential interferences (kit-dependent) |
Specific electrodes | Plasma (without lithium heparin as anticoagulant) or serum | Lithium | |
LC–MS/MS or GC–MS | Plasma or serum | Acetaminophen, salicylic acid (active metabolite of acetylsalicylic acid), digoxin, valproic acid | No interference Not automated, cannot be used in an emergency |
Flame photometer | Plasma or total blood (erythrocyte assay) | Lithium |