Table 2 Fluid administration, balance, perfusion targets and vasopressor dosage in both randomization arms during the study period
CRT targeted group | Lactate targeted group | p-value | |
|---|---|---|---|
Fluid Bolus 6 h (ml) | 875 [375–2625] | 1500 [1000–2000] | 0.3 |
Fluid Balance 6 h (ml) | 982 [249–2833] | 1580 [740–6587] | 0.2 |
Fluid Balance 24 h (ml) | 1710 [614–4172] | 2015 [166–5060] | 0.85 |
CRT 6 h (s) | 3 [2–5] | 3 [2–5] | 0.8 |
CRT 24 h (s) | 3 [2–4] | 3 [2, 3] | 0.9 |
Lactate 6 h (mmol/L) | 2.3 [1.8–4] | 3.5 [1.8–7.3] | 0.4 |
Lactate 24 h (mmol/L) | 2 [1.3–3.2] | 1.9 [1.4—4.3] | 0.9 |
NE dose 6 h (mcg/kg/min | 0.33 [0.11–0.46] | 0.21 [0.12–0-35] | 0.26 |
NE dose 24 h (mcg/kg/min) | 0.14 [0.04–0.32 | 0.13 [0.01–0.25] | 0.6 |