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Annals of Intensive Care

Table 2 Baseline demographics, diagnostic categories, severity of illness scores, type of primary ECLS, non-intubated patients, cannulation configuration according to level of mobilisation

From: Feasibility, safety, and resource utilisation of active mobilisation of patients on extracorporeal life support: a prospective observational study

Variable

Mob

Non-Mob

All

p value

n = 43 (37.4%)

n = 72 (62.6%)

n = 115

Age, BMI, and sex—median (IQR), n (%)

 Age (years)

53.0 (45.0–68.0)

58.5 (47.8–67.0)

57.0 (46.0–67.5)

0.51

 Body mass index (BMI)

24.6 (21.2–27.3)

26.2 (23.2–29.3)

25.6 (22.5–27.8)

0.37

 Female sex (% within subgroup)

15 (34.9)

22 (30.6)

37 (32.2)

0.68

Primary diagnosis—n (% Mob/Non-Mob per subgroup; % between diagnostic groups for ALL)

 ARDS

13 (34.2)

25 (65.8)

38 (33,0)

0.08

 AHF without CS

10 (37.0)

17 (63.0)

27 (23,5)

0.96

 AHF peri/post-CS

6 (35.3)

11 (64.7)

17 (14,8)

0.84

 eCPR

3 (17.6)

14 (82.4)

17 (14,8)

0.10

 COPD

7 (63.6)

4 (36.4)

11 (9,6)

0.09

 ILD

3 (75.0)

1 (25.0)

4 (3,5)

0.14

 PAH

1 (100.0)

0 (0.0)

1 (0,9)

0.37

 ECLS as bridge-to-transplant

2 (100.0)

0 (0.0)

2 (1.7)

0.14

Severity of illness scores—median (IQR)

 SAPS-II score on ICU admission

38 (31–47)

44 (39–54)

42 (36–50)

0.01

 APACHE II score on ICU admission

19 (16–22)

26 (20–30)

23 (18–28)

 < 0.01

 SOFA score on ICU admission

8 (6–11)

11 (8–13)

10 (7–13)

 < 0.01

Type of primary ECLS—n (% Mob/Non-Mob per subgroup; % within ECLS types for ALL)

 va-ECMO (non-eCPR)

14 (29.8)

33 (70.2)

47 (40.9)

 < 0.01

 eCPR (va-ECMO)

3 (17.6)

14 (82.4)

17 (14.8)

0.01

 vv-ECMO

12 (46.2)

14 (53.8)

26 (22.6)

0.84

 vv-ECCO2R

7 (58.3)

5 (41.7)

12 (10.4)

0.77

 av-ECCO2R

3 (33.3)

6 (66.7)

9 (7.8)

0.75

 RVAD

4 (100)

0 (0)

4 (2.6)

0.02

Non-intubated ECLS—n (% Mob/Non-Mob per subgroup; % within ECLS types for ALL)

 All non-intubated patients on ECLS

9 (75.0)

3 (25.0)

12 (10.4)

0.14

Cannulation—n (% Mob/Non-Mob per subgroup; % within cannulation categories for ALL)

 Femoro-femoral

22 (31.0)

49 (69.0)

71 (61.7)

 < 0.01

 DL femoral

2 (100)

0 (0)

2 (1.7)

0.14

 Femoro-jugular

12 (46.2)

14 (53.8)

26 (22.6)

0.85

 DL jugular

3 (75.0)

1 (25.0)

4 (3.5)

0.63

 Femoro-central

4 (44.4)

5 (55.6)

9 (7.8)

0.98

 Central

0 (0)

3 (100)

3 (2.6)

0.29

  1. Data are presented as n (%) for categorical variables and median (25th and 75th percentile) for continuous variables
  2. Mob mobilised with IMS ≥ 3, Non-Mob never mobilised with IMS ≥ 3, ARDS acute respiratory distress syndrome, COPD chronic obstructive pulmonary disease, ILD interstitial lung disease, PAH pulmonary arterial hypertension, AHF acute heart failure, CS cardiac surgery, eCPR extracorporeal cardiopulmonary resuscitation, ECLS extracorporeal life support, ICU intensive care unit, SAPS Simplified Acute Physiology Score, APACHE Acute Physiology and Chronic Health Evaluation, SOFA Sepsis-related Organ Failure Assessment, eCPR extracorporeal cardiopulmonary resuscitation, ECLS extracorporeal life support, va-ECMO veno-arterial extracorporeal membrane oxygenation, vv-ECMO veno-venous extracorporeal membrane oxygenation, vv-ECCO2R veno-venous extracorporeal carbon dioxide removal, av-ECCO2R arterio-venous extracorporeal carbon dioxide removal, RVAD right ventricular assist device, DL double lumen
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