Are single-lumen 5Fr and triple-lumen 6Fr PICCs suitable for hemodynamic assessment by trans-pulmonary thermodilution? A pilot study

Annals of Intensive Care

Table 5 Automated injection phase: Comparison between triple-lumen 6Fr PICC vs. CICC

Variables	6 Fr triple-lumen PICC	CICC	p value	Bias [LoA]	Bias, %	Error, %
Measurements, n	40	40	–	–	–	–
CI, L/min/m²	3.4 (0.7)	3.0 (0.7)	0.012	0.39 [− 0.05; 0.83]	12.5	13.8
GEDVI, mL/m²	689 (117)	622 (89)	0.006	66.5 [− 40; 173]	9.7	16.2
EVLWI, mL/kg	14.3 (5.0)	12.7 (4.5)	0.134	1.6 [− 0.4; 3.7]	12	15.6
SVI, mL/m²	44.6 (8.4)	39.4 (7.5)	0.004	5.2 [− 1.3; 11.7]	12.5	15.5
CVP, mmHg	12 (5.3)	11.1 (4.9)	0.458	–	–	–
ΔT, °C	0.30 (0.07)	0.34 (0.08)	0.008	− 0.05 [− 0.09; 0.00]	–	15.6
Psi	120	115	< 0.0001	–	–	–

Data are reported as mean (standard deviation)
CI: cardiac index; CICC: centrally inserted central catheter; CVP: central venous pressure; EVLWI: extra-vascular lung water index; GEDVI: global end-diastolic volume index; LoA: limits of agreement; PICC: peripherally inserted central catheter; Psi: pound per square inch; SVI: stroke volume index; ΔT: delta temperature