Preoperative endothelial dysfunction in cutaneous microcirculation is associated with postoperative organ injury after cardiac surgery using extracorporeal circulation: a prospective cohort study

Annals of Intensive Care

Table 2 Association between iontophoresis results and a SOFA score > 3 at 48 h

Iontophoresis	Parameter	Total cohort	SOFA > 3	SOFA ≤ 3	P
Acetylcholine	Peak amplitude, LSPU	33.9 [17.0–48.4]	35.5 [24.0–48.3]	26.2 [13.8–49.2]	0.274
	Time to peak, s	111 [88.5–142.7]	133 [104–156]	98 [76–139]	0.016
	Area under the curve within 3 min, PU/s	8980 [6701–11122]	9383 [7525–11102]	8179 [5942–11330]	0.277
Nitroprusside	Peak amplitude, LSPU	34.5 [22.0–49.5]	34.2 [25.0–43.9]	35.4 [16.1–50.2]	0.684
	Time to peak, s	214 [164–245]	225 [182–258]	178 [142–235]	0.054
	Area under the curve within 3 min, PU/s	7922 [6699–9843]	7711 [6363–10172]	8225 [6735–9686]	0.684

Results of iontophoresis are presented with medians [interquartile range]. Presented data have been filtered by subtraction of movement artifact. P values were obtained for patients with and without an event, using the Mann–Whitney U test
Italic value indicates a P value < 0.05
LSPU laser speckle perfusion units, SOFA Sequential Organ Failure Assessment