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Table 3 Outcomes for PICU admission and organ dysfunction

From: Characteristics and risk factors associated with critical illness in pediatric COVID-19

 

PICU admission

N = 30

No PICU admission

N = 47

p value

Outcome: PICU admission

Age

  

0.0152

 >  = 12 years

20 (66.67)

18 (38.30)

 

 < 12 years

10 (33.33)

29 (61.70)

 

Any comorbidity

  

0.2267

 Yes

17 (56.67)

20 (42.55)

 

 No

13 (43.33)

27 (57.45)

 

BMI category (N = 45)a

  

0.7310

 Overweight/obese

7 (35.00)

10 (40.00)

 

 Underweight/normal weight

13 (65.00)

15 (60.00)

 

Laboratory data

   

 Initial CRP (N = 37)

  

0.0053

  Median (IQR)

54.10 (13.90, 161.90)

9.30 (4.00, 33.10)

 

 Initial ferritin (N = 42)

  

0.8495

  Median (IQR)

446.05 (307.35, 809.35)

525.30 (160.20, 1003.00)

 

 Initial WBC (N = 69)

  

0.1455

  Median (IQR)

7.8 (5.4–17.1)

7.8 (4.9–12.3)

 

 Initial platelets

  

0.0612

  Median (IQR)

231 (182–206)

267 (200–419)

 
 

Organ dysfunction

N = 14

No organ dysfunction

N = 63

p value

Outcome: organ dysfunction

   

Age

  

0.2166

 >  = 12 years

9 (64.29)

29 (46.03)

 

 < 12 years

5 (35.71)

34 (53.97)

 

Any comorbidity

  

0.8719

 Yes

7 (50.00)

30 (47.62)

 

 No

7 (50.00)

33 (52.38)

 

BMI category (N = 45)1

  

0.7224

 Overweight/obese

5 (45.45)

12 (35.29)

 

 Underweight/normal weight

6 (54.55)

22 (64.71)

 

Laboratory data

   

 Initial CRPc

  

0.0011

  Median (IQR)

109.70 (54.25, 218.15)

13.90 (4.50, 46.70)

 

 Initial ferritinb

  

0.2125

  Median (IQR)

454.60 (373.70, 1039.00)

487.10 (178.90, 592.40)

 

 Initial WBC (N = 69)

  

0.0341

  Median (IQR)

15.7 (6.4–18.5)

7.8 (4.8–11.4)

 

 Initial platelets

   

  Median (IQR)

149 (100–280)

268 (203–392)

0.0025

  1. Organ dysfunction defined as pSOFA >  = 2, No organ dysfunction included floor patients and ICU patients with pSOFA < 2
  2. aPatients < 2 years old excluded (n = 25) and n = 7 missing >  = 2 years old
  3. bFerritin collected for 42 patients
  4. cCRP collected for 37 patients