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Table 1 Risk factors and consequences of withdrawal syndrome

From: Proceedings of Réanimation 2020, the French Intensive Care Society International Congress

 

WAT-1 ≥ 3

(n = 23)

WAT-1 < 3

(n = 23)

p

Duration of opioids (d)

6.0 (4.9; 5.0)

4.0 (3.0; 5.5)

0.006

Total dose of opioids

(µg/kg equivalent sufentanil)

41.7 (30.9; 127.6)

17.25 (132.0; 35.9)

 < 0.001

Duration of BZD infusion (d)

5.0 (5.0; 9.0)

4.0 (3.0; 5.5)

0.006

Total dose of BZD (mg/kg equivalent midazolam)

33.2 (20.8; 58.9)

14.0 (5.6; 20.4)

 < 0.001

Length of mechanical ventilation (d) 

9.0 (6.5; 13.0)

5.0 (4.0; 7.0)

 < 0.001

Length of stay in the PICU (d)

13.0 (10.0; 23.0)

9.0 (5.0; 10.5)

 < 0.001

Data presented as median (range). BZD: benzodiazepine, d: days, PICU: pediatric intensive care unit. A p value < 0.05 was considered statistically significant.