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Table 1 Risk factors and consequences of withdrawal syndrome

From: Proceedings of Réanimation 2020, the French Intensive Care Society International Congress

 WAT-1 ≥ 3
(n = 23)
WAT-1 < 3
(n = 23)
p
Duration of opioids (d)6.0 (4.9; 5.0)4.0 (3.0; 5.5)0.006
Total dose of opioids
(µg/kg equivalent sufentanil)
41.7 (30.9; 127.6)17.25 (132.0; 35.9) < 0.001
Duration of BZD infusion (d)5.0 (5.0; 9.0)4.0 (3.0; 5.5)0.006
Total dose of BZD (mg/kg equivalent midazolam)33.2 (20.8; 58.9)14.0 (5.6; 20.4) < 0.001
Length of mechanical ventilation (d) 9.0 (6.5; 13.0)5.0 (4.0; 7.0) < 0.001
Length of stay in the PICU (d)13.0 (10.0; 23.0)9.0 (5.0; 10.5) < 0.001
Data presented as median (range). BZD: benzodiazepine, d: days, PICU: pediatric intensive care unit. A p value < 0.05 was considered statistically significant.