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Table 2 Patient characteristics at ICU admission, based on the presence of ventilator-associated lower respiratory tract infections

From: Accuracy of ventilator-associated events for the diagnosis of ventilator-associated lower respiratory tract infections

 

VAP, n = 215

VAT, n = 99

No VA-LRTI, n = 745

p

Male gender

156 (72.5)

66 (66.6)

473 (63.5)

0.001#

Age, years

57 (45–67)

59 (47–69)

61 (49–69.8)

0.041#

SAPS II

59 (48–73)

55 (45–68)

58.5 (46–71)

0.126

SOFA

10 (7–12)

9 (6–11)

9 (6–12)

0.091

Reason for admission

 Medical vs surgical

181 (84.2)

80 (80.8)

622 (83.5)

0.742

 Septic shock

54 (25.1)

17 (17.2)

194 (26)

0.158

 Acute respiratory failure

80 (37.2)

35 (35.4)

260 (34,9)

0.830

 Neurologic failure

53 (24.7)

28 (28.3)

129 (17.3)

0.005#*

 Soft tissue infection

15 (7)

12 (12.1)

79 (10.6)

0.224

 Cardiac arrest

22 (10.2)

10 (10.1)

88 (11.8)

0.741

 Poisoning

8 (3.7)

2 (2)

37 (5)

0.345

 Other

35 (16.3)

12 (12.1)

115 (15.4)

0.624

Charlson comorbidity index

3 (1–5)

3 (1–5)

4 (2–6)

0.660

Diabetes

43 (20)

20 (20.2)

177 (23.8)

0.417

Chronic renal failure

17 (7.9)

13 (13.1)

75 (10.1)

0.343

Chronic heart failure

37 (17.2)

21 (21.2)

132 (17.7)

0.665

Chronic respiratory failure

15 (15.9)

7 (10.9)

57 (14.7)

0.885

Cirrhosis

18 (8.4)

8 (8)

67 (7.7)

0.918

Immunosuppression

59 (27.4)

17 (17.2)

215 (28.9)

0.049*¤

Obesity

 BMI > 30

50 (23.3)

26 (26.3)

141 (18.9)

0.128

 BMI > 35

27 (12.6)

11 (11.1)

78 (10.5)

0.320

  1. Results are numbers (%), or median (interquartile range)
  2. BMI: body mass index; SAPS, simplified acute physiology score; SOFA, sepsis-related organ failure assessment; VA-LRTI, ventilator-associated low respiratory tract infection; VAP, ventilator-associated pneumonia; VAT, ventilator-associated tracheobronchitis
  3. * Significant difference between VAT and no VA-LRTI groups
  4. #Significant difference between VAP and no VA-LRTI groups
  5. ¤Significant difference between VAP and VAT groups