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Table 1 Characteristics and outcomes according to PP-responder status

From: Prone positioning monitored by electrical impedance tomography in patients with severe acute respiratory distress syndrome on veno-venous ECMO

CharacteristicAll patients
(n = 21)
PP responders
(n = 13)
PP non-responders
(n = 8)
P
Age, year56 (46–61)59 (45–62)49 (36–55)0.07
Male, n (%)13 (62)8 (62)5 (63)0.68
BMI (kg/m2)29 (27–39)30 (29–40)27 (23–34)0.046
SAPS II68 (55–79)70 (52–76)66 (57–87)0.59
SOFA13 (11–16)13 (11–16)14 (12–16)0.64
ARDS-risk factor
 Viral pneumonia12 (57)9 (69)3 (38)0.004
 Bacterial pneumonia4 (19)4 (31)0 
 Aspiration pneumonia2 (10)02 (26) 
 Other3 (14)03 (38) 
 MV duration before inclusion (d)8 (6–11)7 (5–9)12 (5–28)0.13
 Tidal volume (mL/kg)4.2 (3.3–5.4)5.1 (3.4–5.9)3.6 (2.7–5.4)0.12
 Static compliance (mL/cmH2O)22.6 (18.1–28.9)23.8 (18.3–33.4)20.1 (8.7–28.0)0.26
 “Optimal PEEP” before PP (cmH2O)14 (12–16)14 (12–17)11 (8–15)0.11
 PP before inclusion (%)16 (76)9 (69)7 (88)0.61
 Median number of PP sessions2 (1, 2)3 (2–4)2 (1–6)0.85
 ECMO duration before inclusion (d)2 (1–5)3 (1–5)1 (1–18)0.65
 ECMO flow (L/min)5.1 (4.3–5.6)5.1 (4.3–5.6)5.1 (4.3–5.7)0.89
 ECMO sweep-gas flow (L/min)5 (3–8)5 (3–7)5 (3–8)0.59
 Fluid balance, mL/24 h480 (− 710 to 1037)600 (− 930 to 1100)1100 (− 180 to 2700)0.80
 MV duration (d)43 (27–62)34 (27–55)59 (46–82)0.06
 ECMO duration (d)16 (11–23)13 (10–19)28 (13–65)0.046
 ICU Length of stay (d)58 (59–71)42 (28–64)69 (59–92)0.02
 In-ICU deaths (%)8 (38)5 (38)3 (38)1
  1. Results are expressed as mean/median (IQR). ARDS acute respiratory distress syndrome, BMI body mass index, d days, ECMO extracorporeal membrane oxygenation, ICU intensive care unit, MV mechanical ventilation, PEEP positive end-expiratory pressure, PP prone positioning, SAPS II Simplified Acute Physiology Score II, SOFA Sequential Organ-Failure Assessment