Table 1 Characteristics and outcomes according to PP-responder status
Characteristic | All patients (n = 21) | PP responders (n = 13) | PP non-responders (n = 8) | P |
|---|---|---|---|---|
Age, year | 56 (46–61) | 59 (45–62) | 49 (36–55) | 0.07 |
Male, n (%) | 13 (62) | 8 (62) | 5 (63) | 0.68 |
BMI (kg/m2) | 29 (27–39) | 30 (29–40) | 27 (23–34) | 0.046 |
SAPS II | 68 (55–79) | 70 (52–76) | 66 (57–87) | 0.59 |
SOFA | 13 (11–16) | 13 (11–16) | 14 (12–16) | 0.64 |
ARDS-risk factor | ||||
Viral pneumonia | 12 (57) | 9 (69) | 3 (38) | 0.004 |
Bacterial pneumonia | 4 (19) | 4 (31) | 0 | |
Aspiration pneumonia | 2 (10) | 0 | 2 (26) | |
Other | 3 (14) | 0 | 3 (38) | |
MV duration before inclusion (d) | 8 (6–11) | 7 (5–9) | 12 (5–28) | 0.13 |
Tidal volume (mL/kg) | 4.2 (3.3–5.4) | 5.1 (3.4–5.9) | 3.6 (2.7–5.4) | 0.12 |
Static compliance (mL/cmH2O) | 22.6 (18.1–28.9) | 23.8 (18.3–33.4) | 20.1 (8.7–28.0) | 0.26 |
“Optimal PEEP” before PP (cmH2O) | 14 (12–16) | 14 (12–17) | 11 (8–15) | 0.11 |
PP before inclusion (%) | 16 (76) | 9 (69) | 7 (88) | 0.61 |
Median number of PP sessions | 2 (1, 2) | 3 (2–4) | 2 (1–6) | 0.85 |
ECMO duration before inclusion (d) | 2 (1–5) | 3 (1–5) | 1 (1–18) | 0.65 |
ECMO flow (L/min) | 5.1 (4.3–5.6) | 5.1 (4.3–5.6) | 5.1 (4.3–5.7) | 0.89 |
ECMO sweep-gas flow (L/min) | 5 (3–8) | 5 (3–7) | 5 (3–8) | 0.59 |
Fluid balance, mL/24 h | 480 (− 710 to 1037) | 600 (− 930 to 1100) | 1100 (− 180 to 2700) | 0.80 |
MV duration (d) | 43 (27–62) | 34 (27–55) | 59 (46–82) | 0.06 |
ECMO duration (d) | 16 (11–23) | 13 (10–19) | 28 (13–65) | 0.046 |
ICU Length of stay (d) | 58 (59–71) | 42 (28–64) | 69 (59–92) | 0.02 |
In-ICU deaths (%) | 8 (38) | 5 (38) | 3 (38) | 1 |